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Protein
Submitted name:

MHC class I antigen

Gene
N/A
Organism
Ovis aries (Sheep)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the presentation of foreign antigens to the immune system.SAAS annotation

GO - Biological processi

Keywordsi

Biological processImmunity

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
OrganismiOvis aries (Sheep)Imported
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei285 – 308HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane, MHC ISAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501287080425 – 334Sequence analysisAdd BLAST310

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini189 – 275Ig-likeInterPro annotationAdd BLAST87

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
IPR010579 MHC_I_a_C
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PF06623 MHC_I_C, 1 hit
PRINTSiPR01638 MHCCLASSI
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1Z1VUS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVMGPRSLL LLLPGAPVLT ETWAGSHSLR YFFTAVSRPG LGEPRFIAVG
60 70 80 90 100
YVDDTQFVRF DSDAPDPRME PRARWVEQEG PEYWDQETQG TKDTALTFRA
110 120 130 140 150
NLNNLRGYYN QSEAGSHTLQ VIYGCDVGPD GRLLHGYDRF AYDGREYIAL
160 170 180 190 200
NEDLRSWTAA DTAAQGECVE WLRRYLETGK DTLQRADPPK AHVTCHPISD
210 220 230 240 250
REVTLRCWAL GFYPEEISLT WQRDEEDQTQ DMELVKTRPS GDGTFQKWAA
260 270 280 290 300
LVVPSEEEQR YTCRVQHQGL QEPLTLRWEP PQTSFLTMGI IVGLVLLMVP
310 320 330
VVAGAVIWRK KHSGDKGESY IQASSCDSAQ GSDV
Length:334
Mass (Da):37,681
Last modified:September 27, 2017 - v1
Checksum:i322788CA42F4A5C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KX853301 Genomic DNA Translation: ARX74124.1

Similar proteinsi

Entry informationi

Entry nameiA0A1Z1VUS0_SHEEP
AccessioniPrimary (citable) accession number: A0A1Z1VUS0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 27, 2017
Last sequence update: September 27, 2017
Last modified: February 28, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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