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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Bordetella genomosp. 8
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei138GTPUniRule annotation1
Binding sitei142GTPUniRule annotation1
Binding sitei186GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi23 – 27GTPUniRule annotation5
Nucleotide bindingi107 – 109GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
ORF Names:CAL12_22385Imported
OrganismiBordetella genomosp. 8Imported
Taxonomic identifieri1416806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000194151 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 204TubulinInterPro annotationAdd BLAST190
Domaini206 – 324Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1W6YQG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNFEMLENS TKGTVIKVVG VGGAGGNAVA HMIRNGVSGV DFICANTDAQ
60 70 80 90 100
ALAATNAPVQ IRLGRTGLGA GAKPEQGRAS AETAREEIRA ALNGAHMVFI
110 120 130 140 150
TAGMGGGTGT GAGPVVAEVA KELGILTVGV VTKPFQFEGN KRLKMAEEGI
160 170 180 190 200
NELAKHVHSL IVVLNENLYE LMDEDATQED CFKSADDILH NACAGIAEII
210 220 230 240 250
NVEGNVNVDF EDVKTIMGEQ GQAMMGTATA SGVDRARVAA EHAIACPLLE
260 270 280 290 300
GIDLHGARGV LVNITASRTL KMRETREIME TIRGYASEDA TVIFGTAYDE
310 320 330 340 350
SMGDSLRVTV VATGLGRTSS RPQLVQSRGE ALRTGTDDFP MVGMVANNGA
360 370 380 390
GQGDYRNLDM PSVMRNPRTQ ASAQVRALES SGMDHFDIPA FLRKQAD
Length:397
Mass (Da):41,835
Last modified:July 5, 2017 - v1
Checksum:i7B43C03BA264EC83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP021108 Genomic DNA. Translation: ARP83297.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1W6YQG7_9BORD
AccessioniPrimary (citable) accession number: A0A1W6YQG7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2017
Last sequence update: July 5, 2017
Last modified: February 28, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported