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Protein

Dihydroneopterin aldolase

Gene

mptD

Organism
Picrophilus oshimae DSM 9789
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).UniRule annotation

Catalytic activityi

7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei20SubstrateUniRule annotation1
Binding sitei114Substrate; via amide nitrogen and carbonyl oxygenUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionLyaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydroneopterin aldolaseUniRule annotation (EC:4.1.2.25UniRule annotation)
Short name:
DHNAUniRule annotation
Alternative name(s):
7,8-dihydroneopterin aldolaseUniRule annotation
Gene namesi
Name:mptDUniRule annotation
ORF Names:SAMN02745355_1515Imported
OrganismiPicrophilus oshimae DSM 9789Imported
Taxonomic identifieri1122961 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesPicrophilaceaePicrophilus
Proteomesi
  • UP000192315 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

SMRiA0A1W2G4W0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 116DHNAInterPro annotationAdd BLAST105

Sequence similaritiesi

Belongs to the archaeal dihydroneopterin aldolase family.UniRule annotation

Family and domain databases

Gene3Di3.30.1300.20, 1 hit
HAMAPiMF_02130 DHNA_arch, 1 hit
InterProiView protein in InterPro
IPR027508 DHN_aldolase_MptD
IPR036839 MptD_sf
IPR007181 MtpD_C
IPR007179 MtpD_N
PfamiView protein in Pfam
PF04038 DHNA, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD027636 DUF372, 1 hit
SUPFAMiSSF143560 SSF143560, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1W2G4W0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYDPAEKYFN CTDIQRAFFE AGIKLGAIFH QYTGIPVNSE NASMAEEFIE
60 70 80 90 100
RSTMIQPFVE NVRISINNVK RSSGTYSYSS LNEKMLHAEV LINYNGKKVL
110 120
GVLNYDEGLD YPVMYAKEVL
Length:120
Mass (Da):13,692
Last modified:June 7, 2017 - v1
Checksum:iFE6A54DA26CF085F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FWYE01000005 Genomic DNA Translation: SMD31564.1
RefSeqiWP_011177019.1, NZ_FWYE01000005.1

Genome annotation databases

GeneIDi2844002

Similar proteinsi

Entry informationi

Entry nameiA0A1W2G4W0_9EURY
AccessioniPrimary (citable) accession number: A0A1W2G4W0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: May 23, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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