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Protein

S-adenosylmethionine:tRNA ribosyltransferase-isomerase

Gene

queA

Organism
Nitrobacter vulgaris
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).UniRule annotationSAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine(34) in tRNA = L-methionine + adenine + epoxyqueuosine(34) in tRNA.UniRule annotationSAAS annotation

Pathwayi: tRNA-queuosine biosynthesis

This protein is involved in the pathway tRNA-queuosine biosynthesis, which is part of tRNA modification.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway tRNA-queuosine biosynthesis and in tRNA modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseImported, TransferaseUniRule annotationSAAS annotationImported
Biological processQueuosine biosynthesisUniRule annotationSAAS annotation
LigandS-adenosyl-L-methionineUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00392.

Names & Taxonomyi

Protein namesi
Recommended name:
S-adenosylmethionine:tRNA ribosyltransferase-isomeraseUniRule annotationSAAS annotation (EC:2.4.99.17UniRule annotationSAAS annotation)
Alternative name(s):
Queuosine biosynthesis protein QueAUniRule annotation
Gene namesi
Name:queAUniRule annotation
ORF Names:B2M20_10470Imported
OrganismiNitrobacter vulgarisImported
Taxonomic identifieri29421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
Proteomesi
  • UP000189940 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the QueA family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_00113. QueA. 1 hit.
InterProiView protein in InterPro
IPR003699. QueA.
IPR036100. QueA_sf.
PANTHERiPTHR30307. PTHR30307. 1 hit.
PfamiView protein in Pfam
PF02547. Queuosine_synth. 1 hit.
SUPFAMiSSF111337. SSF111337. 1 hit.
TIGRFAMsiTIGR00113. queA. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1V4HY65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTDLFDFEL PAESIALRPA SPRDSARMLV VQPGAGLRDQ RVRDLPEWLR
60 70 80 90 100
PGDQLVVNDT RVIAAQLHGR RIGRETEPRI DATLIKRLDG SRWSALVRPA
110 120 130 140 150
KKLMTGDIVR FGNEGRVCFL GHLDAQVESK GEEGEVTFAF SFHGPTLDQA
160 170 180 190 200
IADLGSTPLP PYIASKRAPD DRDAADYQTM FAAHEGAVAA PTAGLHFTPA
210 220 230 240 250
IEAALRERDV GLHRITLHVG AGTFLPVKAE DSAGHRMHSE WGTISAETAA
260 270 280 290 300
ALNATRASGG RIVAVGTTSL RLLESAAGDD GQIAPFTGET AIFITPGYRF
310 320 330 340 350
RAVDILMTNF HLPRSTLFML VSAFSGFETM KHAYAHAIAG GYRFYSYGDA
360
CLLFPDRSDA
Length:360
Mass (Da):39,084
Last modified:June 7, 2017 - v1
Checksum:iF06D23EB1D45FF40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MWPQ01000040 Genomic DNA. Translation: OPH82931.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1V4HY65_NITVU
AccessioniPrimary (citable) accession number: A0A1V4HY65
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: December 20, 2017
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported