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Protein

Glycerol-3-phosphate dehydrogenase [NAD(P)+]

Gene

gpsA

Organism
Corynebacterium jeikeium
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H.UniRule annotationSAAS annotation

Pathwayi: glycerophospholipid metabolism

This protein is involved in the pathway glycerophospholipid metabolism, which is part of Membrane lipid metabolism.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway glycerophospholipid metabolism and in Membrane lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei108NAD; via amide nitrogenUniRule annotation1
Binding sitei108SubstrateUniRule annotation1
Binding sitei142NAD; via amide nitrogenUniRule annotation1
Active sitei193Proton acceptorUniRule annotation1
Binding sitei257NADUniRule annotation1
Binding sitei284NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi8 – 13NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotation
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesisUniRule annotationSAAS annotation, Phospholipid metabolism
LigandNADUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00940.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(P)+]UniRule annotation (EC:1.1.1.94UniRule annotation)
Alternative name(s):
NAD(P)H-dependent glycerol-3-phosphate dehydrogenaseUniRule annotation
Gene namesi
Name:gpsAUniRule annotation
ORF Names:BWP03_00985Imported
OrganismiCorynebacterium jeikeiumImported
Taxonomic identifieri38289 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000189460 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 161NAD_Gly3P_dh_NInterPro annotationAdd BLAST159
Domaini182 – 323NAD_Gly3P_dh_CInterPro annotationAdd BLAST142

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni257 – 258Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
HAMAPiMF_00394. NAD_Glyc3P_dehydrog. 1 hit.
InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH-like_C_sf.
IPR013328. 6PGD_dom2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS00957. NAD_G3PDH. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1V3DRC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQVAVMGAG SWGTTVAKVF ADAGNEVRLW ARRSEVAEDV RDNHRNSAYL
60 70 80 90 100
GDIELPESLT GTSDPAEALD GAEIVVLGVP SQSLRGNLEK WTDADLIGPD
110 120 130 140 150
ASLVSLAKGI EHSSGLRMSQ LISEVACVPS ERVAVLTGPN LAREVAQGQP
160 170 180 190 200
AATVVACTDM DRAKLIQAAV AAPYFRPYTN TDVIGCEIAG TCKNVIALAA
210 220 230 240 250
GIAAGMGFGD NTAATVITRG LAETTRLALE VGADARTLSG LAGMGDLVAT
260 270 280 290 300
CTSTLSRNRR FGEHLGKGET LEEAAASTKG QVAEGVVSSQ SVFELAGKVG
310 320 330
VEMPITEAVV GVCHEAADVQ QVMMGLLGRS RKAE
Length:334
Mass (Da):34,549
Last modified:June 7, 2017 - v1
Checksum:iE4A0B8B6D2D60B32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MTGK01000005 Genomic DNA. Translation: OOD34429.1.
RefSeqiWP_005295387.1. NZ_MTGK01000005.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1V3DRC5_CORJE
AccessioniPrimary (citable) accession number: A0A1V3DRC5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: March 28, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported