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Protein

ATP-dependent RNA helicase DeaD

Gene

deaD

Organism
Haemophilus influenzae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase, RNA-bindingUniRule annotation
Biological processStress responseUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent RNA helicase DeaDUniRule annotation (EC:3.6.4.13UniRule annotation)
Alternative name(s):
Cold-shock DEAD box protein AUniRule annotation
Gene namesi
Name:deaDUniRule annotation
ORF Names:BV935_04455Imported
OrganismiHaemophilus influenzaeImported
Taxonomic identifieri727 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000189053 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 33Q_MOTIFInterPro annotationAdd BLAST29
Domaini36 – 207Helicase ATP-bindingInterPro annotationAdd BLAST172
Domaini231 – 378Helicase C-terminalInterPro annotationAdd BLAST148

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi5 – 33Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family. DeaD subfamily.UniRule annotation

Family and domain databases

CDDicd00079. HELICc. 1 hit.
cd12499. RRM_EcCsdA_like. 1 hit.
Gene3Di3.30.70.330. 1 hit.
HAMAPiMF_00964. DEAD_helicase_DeaD. 1 hit.
InterProiView protein in InterPro
IPR034415. CsdA_RRM.
IPR005580. DbpA/CsdA_RNA-bd_dom.
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR028618. DEAD_helicase_DeaD.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR012677. Nucleotide-bd_a/b_plait_sf.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF03880. DbpA. 1 hit.
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1V2BWN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDKITFNDL GLPEFILKAV SDLGFETPSP IQQACIPHLL SGNDVLGMAQ
60 70 80 90 100
TGSGKTAAFA LPLLAQIDPS EKHPQMLVMA PTRELAIQVA DACEQFVKYA
110 120 130 140 150
HGTRIVTLYG GQRYDIQLRA LKQGAQVVVG TPGRILDHIR RGTLNLSELR
160 170 180 190 200
FIVLDEADEM LRMGFIDDVE TVMAELPENH QTALFSATMP EPIRRITKRF
210 220 230 240 250
MNDPKEVKIK VNNENAPDIE QSCWYVHGVR KNEALLRFLE VEDFDAAIIF
260 270 280 290 300
ARTKTGTLDI TELLEKNGFR SAALNGDMTQ QLREQTLDRL RNGSLDIVVA
310 320 330 340 350
TDVAARGIDI ERISLVVNYD IPLDAESYVH RIGRTGRAGR SGRALLFVEP
360 370 380 390 400
RERRLLRNIE HLMKKGINEV ELPNHLVLQE CRRKKFVAKI TKQLEHHDLE
410 420 430 440 450
QYRSLLEDLF TADQDQEDIA AAMLMLLQGK QKLILPPDPS MEKRRRERNE
460 470 480 490 500
CGDRRENPRS AERRGERKGY GNPRPMDLYR IEVGRADGVE VRHIVGAIAN
510 520 530 540 550
EGDINSRYIG HIKLYDDYTT VELPQGMPKE LLQQFGKTRV LNKQMQMSFL
560 570 580 590 600
GAVKSDNSRG GDDFNGKRKG RGGDFRGERG RNERNGDNRG NRKFNEKSNR
610
TFSDKPRRDR RSSF
Length:614
Mass (Da):69,751
Last modified:June 7, 2017 - v1
Checksum:iFE4ED959C690565D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MTBH01000019 Genomic DNA. Translation: OMP98642.1.
RefSeqiWP_050948859.1. NZ_MTBH01000019.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1V2BWN1_HAEIF
AccessioniPrimary (citable) accession number: A0A1V2BWN1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: March 28, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported