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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Lactobacillus paracasei
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei140GTPUniRule annotation1
Binding sitei144GTPUniRule annotation1
Binding sitei188GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 26GTPUniRule annotation5
Nucleotide bindingi109 – 111GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
ORF Names:A3778_02375Imported, BWK52_1563Imported
OrganismiLactobacillus paracaseiImported
Taxonomic identifieri1597 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000191896 Componenti: Chromosome
  • UP000194992 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 206TubulinInterPro annotationAdd BLAST193
Domaini208 – 325Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1V0Q4A8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFQMDAQNE KGANIKVIGV GGAGGNAINR MIAEDVKGVE FIAANTDLQA
60 70 80 90 100
LNASNAETKI QLGPKLTRGL GAGSNPEIGQ KAAEESEEAI GAALQGADMI
110 120 130 140 150
FVTAGMGGGS GTGAAPIVAK IAKDQGALTV GVVTRPFTFE GPKRAKNATE
160 170 180 190 200
GIAQLKEHVD TLVIIANNRL LEIVDKKTPM LEAFHAADNV LRQGVQGISD
210 220 230 240 250
LITSPGYVNL DFADVKTVMA NQGSALMGIG SATGENRTVE ATKKAISSPL
260 270 280 290 300
LEVNISGAKQ VLLNITGGPD LSLFEAQDAS QIVADSAKDD VNIIFGTSIN
310 320 330 340 350
EELGDEVVVT VIATGIEEDP RQEPSRRNVA KNRTTDQDNQ GGGYRPAYAD
360 370 380 390 400
SDANENRQAK SDDPFGNWDL RREPSKRQAP SGDDISNAKK KDFDIFENQT
410
NADDAGGDDQ PPFFKRRRQ
Length:419
Mass (Da):44,277
Last modified:June 7, 2017 - v1
Checksum:iBAFF2C0671F3CD62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP014985 Genomic DNA. Translation: ARE43007.1.
NCSO01000022 Genomic DNA. Translation: OUC71509.1.
RefSeqiWP_003570127.1. NZ_NOKL01000002.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1V0Q4A8_LACPA
AccessioniPrimary (citable) accession number: A0A1V0Q4A8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: March 28, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported