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Protein
Submitted name:

cadherin-18

Gene

CDH18

Organism
Tarsius syrichta (Philippine tarsier)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cadherins are calcium-dependent cell adhesion proteins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionUniRule annotationSAAS annotation
LigandCalciumUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cadherin-18Imported
Gene namesi
Name:CDH18Imported
OrganismiTarsius syrichta (Philippine tarsier)Imported
Taxonomic identifieri1868482 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniTarsiiformesTarsiidaeCarlito
Proteomesi
  • UP000189704 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei562 – 583HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 104CAInterPro annotationAdd BLAST82
Domaini128 – 213CAInterPro annotationAdd BLAST86
Domaini237 – 329CAInterPro annotationAdd BLAST93
Domaini352 – 433CAInterPro annotationAdd BLAST82
Domaini456 – 543CAInterPro annotationAdd BLAST88

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di4.10.900.10, 1 hit
InterProiView protein in InterPro
IPR002126 Cadherin
IPR015919 Cadherin-like
IPR020894 Cadherin_CS
IPR000233 Cadherin_cytoplasmic-dom
IPR027397 Catenin_binding_dom_sf
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF01049 Cadherin_C, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 5 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 2 hits

Sequencei

Sequence statusi: Complete.

A0A1U7UUM8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRECDVRLE YNCMLTYSMC LLQLHSNSDK GDGSVKYILT GEGAGTIFII
60 70 80 90 100
DDTTGDIHST KSLDREQKTH YVLHAQAIDR RTNKPLEPES EFIIKVQDIN
110 120 130 140 150
DNAPKFTDGP YIVTVPEMSD MGTSVLQVTA TDADDPTYGN SARVVYSILQ
160 170 180 190 200
GQPYFSVDPK TGVIRTALHN MDREAREHYS VVIQAKDMAG QVGGLSGSTT
210 220 230 240 250
VNITLTDVND NPPRFPQKHY QLYVPESAQV GSAVGKIKAN DADTGSNADM
260 270 280 290 300
TYSIINGDGI GIFSISTDRE TREGILSLKK PLNYEKKKSY TLNIEGANTH
310 320 330 340 350
LDFRFSHLGP FKDATMLKII VGDVDEPPQF SMPSYDMEVY ENAKIGTIVG
360 370 380 390 400
TVLAQDPDSA NSLVRYFINY NAEEDRFFNI DANTGTIKTT RVLDREETPW
410 420 430 440 450
YNITVAASEN DNPGLLSHVT VGIRVLDVND NPPELAREYD IVVCENSKPG
460 470 480 490 500
QVIHTISATD KDDFANGPRF NFFLDERLPL NPNFTLKDNE DNTASILTRR
510 520 530 540 550
RRFSRSIQDV YYLPIMISDG GIPSLSSSST LTIRVCACER DGRVRTCHAE
560 570 580 590 600
AFLSSAGLST GALIAILLCV VILLAIVVLF ITLRRSKKEP LIISEEDVRE
610 620 630 640 650
NVVTYDDEGG GEEDTEAFDI TALRNPSAAE ELKYRRDIRP EVKLTPRHQT
660 670 680 690 700
LSTLESIDVQ EFIKQRLAEA DLDPSVPPYD SLQTYAYEGQ RSEAGSISSL
710 720 730
DSATTQSDQD YHYLGDWGPE FKKLAELYGE IESERTT
Length:737
Mass (Da):82,016
Last modified:May 10, 2017 - v1
Checksum:i833EE8F5A3C1CAFF
GO

Sequence databases

RefSeqiXP_008069576.1, XM_008071385.1

Genome annotation databases

GeneIDi103273921

Similar proteinsi

Entry informationi

Entry nameiA0A1U7UUM8_TARSY
AccessioniPrimary (citable) accession number: A0A1U7UUM8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: February 28, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health