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Protein
Submitted name:

beta-2 adrenergic receptor

Gene

Adrb2

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
beta-2 adrenergic receptorImported
Gene namesi
Name:Adrb2Imported
OrganismiMesocricetus auratus (Golden hamster)Imported
Taxonomic identifieri10036 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
Proteomesi
  • UP000189706 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei31 – 58HelicalSequence analysisAdd BLAST28
Transmembranei70 – 96HelicalSequence analysisAdd BLAST27
Transmembranei108 – 129HelicalSequence analysisAdd BLAST22
Transmembranei150 – 169HelicalSequence analysisAdd BLAST20
Transmembranei198 – 219HelicalSequence analysisAdd BLAST22
Transmembranei275 – 295HelicalSequence analysisAdd BLAST21
Transmembranei307 – 327HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Structurei

3D structure databases

SMRiA0A1U7Q3C3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 326G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST277

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

CDDicd15957. 7tmA_Beta2_AR. 1 hit.
InterProiView protein in InterPro
IPR002233. ADR_fam.
IPR000332. ADRB2_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PANTHERiPTHR24248:SF21. PTHR24248:SF21. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR01103. ADRENERGICR.
PR00562. ADRENRGCB2AR.
PR00237. GPCRRHODOPSN.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1U7Q3C3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPPGNDSDF LLTTNGSHVP DHDVTEERDE AWVVGMAILM SVIVLAIVFG
60 70 80 90 100
NVLVITAIAK FERLQTVTNY FITSLACADL VMGLAVVPFG ASHILMKMWN
110 120 130 140 150
FGNFWCEFWT SIDVLCVTAS IETLCVIAVD RYIAITSPFK YQSLLTKNKA
160 170 180 190 200
RMVILMVWIV SGLTSFLPIQ MHWYRATHQK AIDCYHKETC CDFFTNQAYA
210 220 230 240 250
IASSIVSFYV PLVVMVFVYS RVFQVAKRQL QKIDKSEGRF HSPNLGQVEQ
260 270 280 290 300
DGRSGHGLRR SSKFCLKEHK ALKTLGIIMG TFTLCWLPFF IVNIVHVIQD
310 320 330 340 350
NLIPKEVYIL LNWLGYVNSA FNPLIYCRSP DFRIAFQELL CLRRSSSKAY
360 370 380 390 400
GNGYSSNSNG KTDYMGEASG CQLGQEKESE RLCEDPPGTE SFVNCQGTVP
410
SLSLDSQGRN CSTNDSPL
Length:418
Mass (Da):46,861
Last modified:May 10, 2017 - v1
Checksum:i9B20478F91FB284E
GO

Sequence databases

RefSeqiNP_001268877.1. NM_001281948.1.

Genome annotation databases

GeneIDi101836719.

Similar proteinsi

Entry informationi

Entry nameiA0A1U7Q3C3_MESAU
AccessioniPrimary (citable) accession number: A0A1U7Q3C3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: October 25, 2017
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported