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Protein

EEF1A lysine methyltransferase 1

Gene

EEF1AKMT1

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.UniRule annotation

Caution

Was originally thought to be an N6-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
EEF1A lysine methyltransferase 1UniRule annotation (EC:2.1.1.-UniRule annotation)
Alternative name(s):
N(6)-adenine-specific DNA methyltransferase 2UniRule annotation
Protein-lysine N-methyltransferase N6AMT2UniRule annotation
Gene namesi
Name:EEF1AKMT1UniRule annotationImported
Synonyms:N6AMT2UniRule annotation
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.UniRule annotation

Family and domain databases

HAMAPiMF_03187 Methyltr_EFM5, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR019369 Efm5/EEF1AKMT1
IPR029063 SAM-dependent_MTases
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS00092 N6_MTASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1S3WJC6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDSEDDNIP QLSAHTLAAL QEFYDEQKQQ TGLCVVGEER YNVGVIEENW
60 70 80 90 100
QLSQFWYSPE TALRLAEEAI AAAGKGGRIA CVSAPSVYQK LRELRGNSIS
110 120 130 140 150
VCLLEYDRRF AIYGEEFIFY DYHHPLDLPD HLTAHSFDLV IADPPYLSSE
160 170 180 190 200
CLQKTAETIK HLTQGRVLLC TGAVMEEEAA RLLGVRMCKF IPKHSWTLAN
210
EFRCYVNYDS GLDGDM
Length:216
Mass (Da):24,451
Last modified:April 12, 2017 - v1
Checksum:i8D1694C979C94100
GO

Sequence databases

RefSeqiXP_016046487.1, XM_016191001.1
XP_016046488.1, XM_016191002.1

Genome annotation databases

GeneIDi103119224

Similar proteinsi

Entry informationi

Entry nameiA0A1S3WJC6_ERIEU
AccessioniPrimary (citable) accession number: A0A1S3WJC6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: December 20, 2017
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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