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Protein

Uridine phosphorylase

Gene

LOC106594171

Organism
Salmo salar (Atlantic salmon)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.UniRule annotation

Catalytic activityi

Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.UniRule annotation

Pathwayi: UMP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes uracil from uridine (phosphorylase route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Uridine phosphorylase (UPP1), Uridine phosphorylase (LOC106594171), Uridine phosphorylase (LOC106586173)
This subpathway is part of the pathway UMP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes uracil from uridine (phosphorylase route), the pathway UMP biosynthesis via salvage pathway and in Pyrimidine metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

UniPathwayiUPA00574; UER00633.

Names & Taxonomyi

Protein namesi
Recommended name:
Uridine phosphorylaseUniRule annotation (EC:2.4.2.3UniRule annotation)
Gene namesi
Name:LOC106594171Imported
OrganismiSalmo salar (Atlantic salmon)Imported
Taxonomic identifieri8030 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeSalmo
Proteomesi
  • UP000087266 Componenti: Genome assembly

Subcellular locationi

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 274PNP_UDP_1InterPro annotationAdd BLAST217

Sequence similaritiesi

Belongs to the PNP/UDP phosphorylase family.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
IPR010059. Uridine_phosphorylase_euk.
PfamiView protein in Pfam
PF01048. PNP_UDP_1. 1 hit.
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR01719. euk_UDPppase. 1 hit.
PROSITEiView protein in PROSITE
PS01232. PNP_UDP_1. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1S3QMQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPGPGFSDE KNETLCESES TVYVHNPHLD GMKEDILYHF NLGTSTHNLP
60 70 80 90 100
AMFGDVKFVC VGGSPWRMKS FIEYIAGELS LEDPKAEYPN ICAGTDRYAM
110 120 130 140 150
YKIGPVLSVS HGMGIPSIAI MLHELIKLLY HARCTDVTIV RIGTSGGLGL
160 170 180 190 200
EPGTVVVTKQ SVDATFLPRL EQVILGNAVV RSTDLDQGLA EELLQCSKDL
210 220 230 240 250
GQFETVIGNT MCTMDFYEGQ ARLDGAFCSY TEKDKQDYLT KAYESGVRNI
260 270 280
EMESSVFAAM CKLSGLKAAV VCVTLLDRQK GDQLS
Length:285
Mass (Da):31,175
Last modified:April 12, 2017 - v1
Checksum:i52961FDC01ACE2DD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei285Imported1

Sequence databases

RefSeqiXP_014041012.1. XM_014185537.1.

Genome annotation databases

GeneIDi106594171.

Similar proteinsi

Entry informationi

Entry nameiA0A1S3QMQ1_SALSA
AccessioniPrimary (citable) accession number: A0A1S3QMQ1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: August 30, 2017
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported