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Protein
Submitted name:

glutamate receptor ionotropic, NMDA 3A isoform X1

Gene

Grin3a

Organism
Dipodomys ordii (Ord's kangaroo rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotationImported
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
glutamate receptor ionotropic, NMDA 3A isoform X1Imported
Gene namesi
Name:Grin3aImported
OrganismiDipodomys ordii (Ord's kangaroo rat)Imported
Taxonomic identifieri10020 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaCastorimorphaHeteromyidaeDipodomyinaeDipodomys
Proteomesi
  • UP000081671 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei676 – 696HelicalSequence analysisAdd BLAST21
Transmembranei717 – 735HelicalSequence analysisAdd BLAST19
Transmembranei747 – 770HelicalSequence analysisAdd BLAST24
Transmembranei935 – 957HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_501018254727 – 1134Sequence analysisAdd BLAST1108

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini557 – 911PBPeInterPro annotationAdd BLAST355
Domaini570 – 623Lig_chan-Glu_bdInterPro annotationAdd BLAST54

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1091 – 1118Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. [View classification]SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR001828 ANF_lig-bd_rcpt
IPR019594 Glu/Gly-bd
IPR001508 Iono_rcpt_met
IPR001320 Iontro_rcpt
IPR028082 Peripla_BP_I
PfamiView protein in Pfam
PF01094 ANF_receptor, 1 hit
PF00060 Lig_chan, 1 hit
PF10613 Lig_chan-Glu_bd, 1 hit
PRINTSiPR00177 NMDARECEPTOR
SMARTiView protein in SMART
SM00918 Lig_chan-Glu_bd, 1 hit
SM00079 PBPe, 1 hit
SUPFAMiSSF53822 SSF53822, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1S3FS95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRLSLWWLL SRVCLLLPPP WALVLAGVPG SSSHPQPCQI LKRIGHAVRV
60 70 80 90 100
GAVHLQPWTT TTPRATSRAP DSSRADAQRD EPEPGTWWPP VPSQGTHRLG
110 120 130 140 150
SALHGRGPPG ARKPDEGTGA ETLWPRDALL FAVDNLNRVE GLLPYNLSLE
160 170 180 190 200
VVMAIEAGLG DLPLLPFSSP SSPWSSDPFS FLQSVCHTVV VQGVSALLAF
210 220 230 240 250
PQSQGEMMEL DLVSSVLHIP VISIVRHEFP RESQNPLHLQ LSLENSFSSD
260 270 280 290 300
ADVTVSILAM NNWYNFSLLL CREDWNITDF LLLIQNNSKF HLGSIINTTA
310 320 330 340 350
GLSFTNNLLS FLQVQLENVK NSTPTIVMFG CNMESIQQIF EMATQFGLTP
360 370 380 390 400
PELHWVLGDS QNVEELRTEG LPLGLIAHGK TTQSFFEYYV QDAMELVARA
410 420 430 440 450
VATATMIQPE LALIPSTMNC MDVKTTNLTS GQYLSRFLAN TTFRGLSGSV
460 470 480 490 500
RVKGSTIISS ENNFFIWNLQ HDPMGKPMWT RLGSWQGGKI VMDYGIWPEQ
510 520 530 540 550
AQRHKTHFQH PNKLHLRVVT LIEHPFVFTR EVDDEGLCPA GQLCLDPMTN
560 570 580 590 600
DSSILDSLFS SLHSGNDTVP IQFKKCCYGY CIDLLEQLAE DMNFDFDLYI
610 620 630 640 650
VGDGKYGAWK NGHWTGLVGD LLSGTAHMAV TSFSINTARS QVIDFTSPFF
660 670 680 690 700
STSLGILVRT RDTAAPIGAF MWPLHWTMWL GIFVALHITA IFLTLYEWKS
710 720 730 740 750
PFGMTPKGRN RSKVFSFSSA LNVCYALLFG RTVAIKPPKC WTGRFLMNLW
760 770 780 790 800
AIFCMFCLST YTANLAAVMV GEKIYEELSG IHDPKLHHPS QGFRFGTVRE
810 820 830 840 850
SSAEDYVRQS FPEMHEYMRR YNVPATPDGV QYLKNDPEKL DAFIMDKALL
860 870 880 890 900
DYEVSIDADC KLLTVGKPFA IEGYGIGLPP NSPLTSNISE LISQYKSHGF
910 920 930 940 950
MDVLHDKWYK VVPCGKRSFA VTETLQMGIK HFSGLFVLLC IGFGLSILTT
960 970 980 990 1000
IGEHIVYRLL LPRIKNKSKL QYWLHTSQRL HRALNTSFVE EKQQRFKTKR
1010 1020 1030 1040 1050
VEKSTWRTAD WKVNLNCLLF PRSNLGPRQL MVWNTSNLSH DNQRKYIFSD
1060 1070 1080 1090 1100
EGGQNQLGIP THQDIPLPPR RRELPASLAT NGRADPLNKA RNSVMQELSE
1110 1120 1130
LEKQIQVIRQ ELHLAVSRKA ELEEYQRTNR TCEA
Length:1,134
Mass (Da):127,624
Last modified:April 12, 2017 - v1
Checksum:i2A83F89D0041BD52
GO

Sequence databases

RefSeqiXP_012878727.1, XM_013023273.1

Genome annotation databases

GeneIDi105990786

Similar proteinsi

Entry informationi

Entry nameiA0A1S3FS95_DIPOR
AccessioniPrimary (citable) accession number: A0A1S3FS95
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: April 25, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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