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Protein
Submitted name:

estrogen receptor beta isoform X1

Gene

ESR2

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi165 – 240Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
estrogen receptor beta isoform X1Imported
Gene namesi
Name:ESR2Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini165 – 240Nuclear receptorInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family. NR3 subfamily.UniRule annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR028355. ER-beta/gamma.
IPR021064. Estrogen_rcpt_beta_N.
IPR035500. NHR_like_dom_sf.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR024178. Oest_rcpt/oest-rel_rcp.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF12497. ERbeta_N. 1 hit.
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PIRSFiPIRSF500102. ER-b. 1 hit.
PIRSF002527. ER-like_NR. 1 hit.
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 2 hits.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1S3AA33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLCTSSHKE FSQLLSIQDM DIKNSPSSLN SPASYNCSQS VLPLEHGPIY
60 70 80 90 100
IPSSYVENRH EYSTMTFYSP AVMNYSIPSS ANISEGGPGR QTAGSNVLWP
110 120 130 140 150
TPGHLSPLSI HCQPSLLYAE PQKSPWCEAR SLEHTLPINR EALKRKVSRS
160 170 180 190 200
SCASPVTSPS TKKDAHFCAV CSDYASGYHY GVWSCEGCKA FFKRSIQGHN
210 220 230 240 250
DYICPATNQC TIDKNRRKSC QACRLRKCYE VGMVKCGSRR ERCGYRILRR
260 270 280 290 300
QRNSDEQLHC LSKAKKNGGH VTRVKELLLN SLSPEQLVLT LLEAEPPNVL
310 320 330 340 350
VSRPNTPFTE ASMMMSLTKL ADKELVHMIG WAKKIPGFVE LSLYDQVRLL
360 370 380 390 400
ESCWMEVLMV GLMWRSIDHP GKLIFAPDLV LDRDEGKCVE GILEIFDMLL
410 420 430 440 450
ATTSRFRELK LQHKEYLCVK AMILLNSSMY PLAAATQEGE SSQKLTHLLN
460 470 480 490 500
AVTDALVWVI AKSGISSQQQ SVRLANLLML LSHVRHASNK GMEHLLSMKC
510 520 530 540
KNVVPVYDLL LEMLNAHTLR GYKSSVTRSE CSPAENSKSK EGSHNPQSQ
Length:549
Mass (Da):61,391
Last modified:April 12, 2017 - v1
Checksum:iD7DD4E9F29516805
GO

Sequence databases

RefSeqiXP_007531776.1. XM_007531714.1.

Genome annotation databases

GeneIDi103121198.

Similar proteinsi

Entry informationi

Entry nameiA0A1S3AA33_ERIEU
AccessioniPrimary (citable) accession number: A0A1S3AA33
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: January 31, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported