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Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Xylella fastidiosa 32
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotationSAAS annotation

Pathwayi: 7,8-dihydroneopterin triphosphate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes 7,8-dihydroneopterin triphosphate from GTP.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. GTP cyclohydrolase 1 (folE), GTP cyclohydrolase FolE2 (folE2)
This subpathway is part of the pathway 7,8-dihydroneopterin triphosphate biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 7,8-dihydroneopterin triphosphate from GTP, the pathway 7,8-dihydroneopterin triphosphate biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei156May be catalytically importantUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

UniPathwayiUPA00848; UER00151

Names & Taxonomyi

Protein namesi
Recommended name:
GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
Gene namesi
Name:folE2UniRule annotation
ORF Names:B398_04600Imported
OrganismiXylella fastidiosa 32Imported
Taxonomic identifieri1214121 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
Proteomesi
  • UP000018676 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the GTP cyclohydrolase IV family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_01527_B GTP_cyclohydrol_B, 1 hit
InterProiView protein in InterPro
IPR022838 GTP_cyclohydrolase_FolE2
IPR003801 GTP_cyclohydrolase_FolE2/MptA
PANTHERiPTHR36445 PTHR36445, 1 hit
PfamiView protein in Pfam
PF02649 GCHY-1, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1S0V9W6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSTSIPDVA VHDSPAVAAP LRWVGMDGIV VPVQLTTADG GQHVIGRARA
60 70 80 90 100
QIDLPAMEVK GIHMSRLYRL LDTHAVEPLT PVGICGLLSA MVNSHADCAS
110 120 130 140 150
TAARVDWHFD WLRRVPALVS NDLSGWRGYP VSLRAEYSAV HVQFWLCVEV
160 170 180 190 200
GYSSTCPCSA ALARQMLADA FLQEHVEVSA LSPETVADWL RSNGSYATPH
210 220 230 240 250
SQRSVARIEV ALTEQAVELG LPALVDCAER ILSTPVQAAV RRVDEQAFAR
260 270 280 290
LNGANLMYVE DATRRLQHGL AIHYSAFRVH VRHLESLHPH DAVASTADE
Length:299
Mass (Da):32,591
Last modified:April 12, 2017 - v1
Checksum:i8DEA97A98098FC0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AWYH01000018 Genomic DNA Translation: ETE33482.1

Similar proteinsi

Entry informationi

Entry nameiA0A1S0V9W6_XYLFS
AccessioniPrimary (citable) accession number: A0A1S0V9W6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: October 25, 2017
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported