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Protein

Transaldolase

Gene

tal

Organism
Escherichia coli N40607
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotationSAAS annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (tal), Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei131Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationSAAS annotationImported
Biological processPentose shuntUniRule annotationSAAS annotation
LigandSchiff baseUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotationSAAS annotation (EC:2.2.1.2UniRule annotationSAAS annotation)
Gene namesi
Name:talUniRule annotation
ORF Names:Q676_24145Imported
OrganismiEscherichia coli N40607Imported
Taxonomic identifieri1416676 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.SAAS annotation

Structurei

3D structure databases

SMRiA0A1R1T5W7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd00957. Transaldolase_TalAB. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00492. Transaldolase_1. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR001585. TAL/FSA.
IPR004730. Transaldolase_1.
IPR018225. Transaldolase_AS.
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiView protein in Pfam
PF00923. TAL_FSA. 1 hit.
TIGRFAMsiTIGR00874. talAB. 1 hit.
PROSITEiView protein in PROSITE
PS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1R1T5W7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNELDGIKQF TTVVADSGDI ESIRHYHPQD ATTNPSLLLK AAGLSQYEHL
60 70 80 90 100
IDDAIAWGKK NGKTQEQQVV AACDKLAVNF GAEILKIVPG RVSTEVDARL
110 120 130 140 150
SFDKEKSIEK ARHLVDLYQQ QGVEKSRILI KLASTWEGIR AAEELEKEGI
160 170 180 190 200
NCNLTLLFSF AQARACAEAG VFLISPFVGR IYDWYQARKP MDPYVVEEDP
210 220 230 240 250
GVKSVRNIYD YYKQHHYETI VMGASFRRTE QILALTGCDR LTIAPNLLKE
260 270 280 290 300
LQEKVSPVVR KLIPPSQTFP RPAPMSEAEF RWEHNQDAMA VEKLSEGIRL
310
FAVDQRKLED LLAAKL
Length:316
Mass (Da):35,659
Last modified:April 12, 2017 - v1
Checksum:i990B00ED7937CF19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AZCG01000145 Genomic DNA. Translation: OMI45933.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1R1T5W7_ECOLX
AccessioniPrimary (citable) accession number: A0A1R1T5W7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: September 27, 2017
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported