Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamate--tRNA ligase

Gene

gltX

Organism
Leptolyngbya sp. 'hensonii'
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).UniRule annotationSAAS annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei251ATPUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationSAAS annotation, Ligase
Biological processProtein biosynthesisUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligaseUniRule annotation (EC:6.1.1.17UniRule annotation)
Alternative name(s):
Glutamyl-tRNA synthetaseUniRule annotation
Short name:
GluRSUniRule annotation
Gene namesi
Name:gltXUniRule annotation
ORF Names:BST81_06290Imported
OrganismiLeptolyngbya sp. 'hensonii'Imported
Taxonomic identifieri1922337 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesLeptolyngbyaceaeLeptolyngbya
Proteomesi
  • UP000186296 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 318tRNA-synt_1cInterPro annotationAdd BLAST316

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi9 – 19"HIGH" regionUniRule annotationAdd BLAST11
Motifi248 – 252"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd00808. GluRS_core. 1 hit.
Gene3Di1.10.10.350. 1 hit.
1.10.8.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00022. Glu_tRNA_synth_type1. 1 hit.
InterProiView protein in InterPro
IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020752. aa-tRNA-synth_I_codon-bd_sub1.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR033910. GluRS_core.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1Q8ZGP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVRVRLAPS PTGNLHIGTA RTGVFNWLFA RHHGGQFILR IEDTDLERSR
60 70 80 90 100
PEFTQNILDG LTWLGLTWDE GPFFQSKRMD LYKAAIQTLL DQGLAYRAYD
110 120 130 140 150
TPEELEALRA SQTARKQAPR YDNRHRHLSP EQEAAYVAEG RQPVIRFKID
160 170 180 190 200
DDREITWTDL VRGPVTWKGS DLGGDMVIAR AAMAPELGQP LYNFVVVVDD
210 220 230 240 250
IDMQITHVIR GEDHIANTAK QILLYEAMGA AVPRFAHTPL ILDQGGRKLS
260 270 280 290 300
KRNGVTSIDD FRKMGYTSEG LVNYMTLLGW SPPDSTQELF RLQEAAQQFD
310 320 330 340 350
FERVNPAGAK FDWAKLDWIN SQYLHRLSVP EMTDLLIPFW QAAGYLFDPL
360 370 380 390 400
ADRPWLEQLG ALVGPSLVRL PVSDPTWMAQ VREIIGPALP AVADGVEMVR
410 420 430 440 450
FLFADPFEFM PEAAKQLEQV GSATALQAIV TLLEQETEAL TEARAKAILD
460 470 480 490 500
QVVQAQNLKR GLVMKSLRAT LTGQLQGPDL MQSWLLLHQR GQDRPRLQQA

LTIAK
Length:505
Mass (Da):56,873
Last modified:April 12, 2017 - v1
Checksum:iDCADF8D77FE5A7E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MQTZ01000017 Genomic DNA. Translation: OLP19355.1.
RefSeqiWP_075597680.1. NZ_MQTZ01000017.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1Q8ZGP9_9CYAN
AccessioniPrimary (citable) accession number: A0A1Q8ZGP9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: March 28, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported