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Protein

Malate dehydrogenase

Gene

mdh

Organism
Sphingobacteriales bacterium 39-19
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reversible oxidation of malate to oxaloacetate.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

(S)-malate + NAD+ = oxaloacetate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei32NADUniRule annotation1
Binding sitei82SubstrateUniRule annotation1
Binding sitei88SubstrateUniRule annotation1
Binding sitei95NADUniRule annotation1
Binding sitei120SubstrateUniRule annotation1
Binding sitei151SubstrateUniRule annotation1
Active sitei175Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi7 – 12NADUniRule annotation6
Nucleotide bindingi118 – 120NADUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotation
Biological processTricarboxylic acid cycleUniRule annotationSAAS annotation
LigandNADUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
Gene namesi
Name:mdhUniRule annotation
ORF Names:BGO53_03725Imported
OrganismiSphingobacteriales bacterium 39-19Imported
Taxonomic identifieri1895834 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesSphingobacteriiaSphingobacteriales
Proteomesi

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 142Ldh_1_NInterPro annotationAdd BLAST142
Domaini147 – 304Ldh_1_CInterPro annotationAdd BLAST158

Sequence similaritiesi

Belongs to the LDH/MDH superfamily. MDH type 3 family.UniRule annotation

Family and domain databases

CDDicd01339 LDH-like_MDH, 1 hit
Gene3Di3.90.110.10, 1 hit
HAMAPiMF_00487 Malate_dehydrog_3, 1 hit
InterProiView protein in InterPro
IPR001557 L-lactate/malate_DH
IPR022383 Lactate/malate_DH_C
IPR001236 Lactate/malate_DH_N
IPR015955 Lactate_DH/Glyco_Ohase_4_C
IPR011275 Malate_DH_type3
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF02866 Ldh_1_C, 1 hit
PF00056 Ldh_1_N, 1 hit
PIRSFiPIRSF000102 Lac_mal_DH, 1 hit
PRINTSiPR00086 LLDHDRGNASE
SUPFAMiSSF51735 SSF51735, 1 hit
SSF56327 SSF56327, 1 hit
TIGRFAMsiTIGR01763 MalateDH_bact, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1Q3TXR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVTVVGAGA VGATCADNIA RKQICDELVI VDIKEGVAEG KAMDLMQTAQ
60 70 80 90 100
IEGFDTRIIG STNDYSKTAG SSVAVITSGI PRKPGMTREE LIGINAGIVK
110 120 130 140 150
SVTENILKHS PDCIIIIISN PMDTMTYLAL KSSGLPKNRI IGMGGILDSA
160 170 180 190 200
RFRYFLSQAI PCSPNDLQAN VIGGHGDTTM IPLTRLATYC GNPVSEFLDD
210 220 230 240 250
EQAQKVAANT MVGGATLTGL LGTSAWYAPG AAGAMLVEAI VRDEKKMVPC
260 270 280 290 300
CVYLEGEYGQ KDICIGVPVI IGKNGWEKII DFKLNDQEKE MFNKSADAVR
310
KMNETLATLS
Length:310
Mass (Da):33,027
Last modified:April 12, 2017 - v1
Checksum:i15A6AF8EBE0F5CD1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MKTX01000017 Genomic DNA Translation: OJW07756.1

Similar proteinsi

Entry informationi

Entry nameiA0A1Q3TXR5_9SPHI
AccessioniPrimary (citable) accession number: A0A1Q3TXR5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: March 28, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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