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Protein

Arginine--tRNA ligase

Gene

argS_1

Organism
Mycobacterium abscessus subsp. abscessus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argS_1Imported
Synonyms:argSUniRule annotationImported, argS_2Imported
ORF Names:SAMEA2070599_04710Imported, SAMEA2070698_04784Imported, SAMEA2070827_02589Imported, SAMEA2071243_00097Imported, SAMEA2071298_03650Imported, SAMEA2071448_04318Imported, SAMEA2071544_02258Imported, SAMEA2071560_04899Imported, SAMEA2145025_04920Imported, SAMEA2161603_02058Imported, SAMEA2259605_00827Imported, SAMEA2275679_00540Imported, SAMEA2275790_04294Imported, SAMEA2275805_04001Imported, SAMEA2275861_02401Imported
OrganismiMycobacterium abscessus subsp. abscessusImported
Taxonomic identifieri1185650 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium abscessus
Proteomesi
  • UP000184667 Componenti: Unassembled WGS sequence
  • UP000214601 Componenti: Unassembled WGS sequence
  • UP000185223 Componenti: Unassembled WGS sequence
  • UP000190703 Componenti: Unassembled WGS sequence

Subcellular locationi

A0A1M8YN24:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 93Arg_tRNA_synt_NInterPro annotationAdd BLAST90
Domaini429 – 550DALR_1InterPro annotationAdd BLAST122

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi130 – 140"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1M8YN24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPADLADLL RSTATTVLDE RGLDTSALPA VVTVERPRNP EHGDYATNVA
60 70 80 90 100
LQVAKKVGVA PRDLAGWLVE ALVSHAAIAG AEIAGPGFVN LRIAADAQGT
110 120 130 140 150
IVANILKAGE TYGNSDAQGT HTINLEFVSA NPTGPIHIGG TRWAAVGDAL
160 170 180 190 200
GRLLARQGAK VTREYYFNDH GAQIDRFVRS LIASAEGKEA PEDGYAGDYI
210 220 230 240 250
ADIAKQVITQ RPEALTLTEP ERSEVFREIG VDLMFTHIKE SLHEFGTDFD
260 270 280 290 300
VFTHEDSMHT SGRVQEAIAQ LRKTGNIYEK DGASWLRSSN FGDDKDRVVI
310 320 330 340 350
KSDGNPAYIA GDIAYYLDKR ERGFDLCIYM LGADHHGYIA RLKAVAAALG
360 370 380 390 400
YDADSVEVLI GQMVNLVRDG QPVRMSKRAG TVITLDDLVD AIGVDAARYA
410 420 430 440 450
LIRSSVDTSI DIDLELWASA SSENPVYYVQ YAHARLCALA RNAADLGLQH
460 470 480 490 500
STEHLELLTH EKEGALIRGL GEFGRILQNA AALREPHRVA RYLEDIAGDY
510 520 530 540 550
HRFYDSCRVL PQGDETPGDL HAARLALCLA TRQVIANGLD ILGVSAPERM
Length:550
Mass (Da):59,679
Last modified:March 15, 2017 - v1
Checksum:iCB0FE1DE15A92015
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FSAD01000009 Genomic DNA. Translation: SHQ76068.1.
FSCO01000009 Genomic DNA. Translation: SHT57943.1.
FSFO01000001 Genomic DNA. Translation: SHX69694.1.
FSGQ01000017 Genomic DNA. Translation: SIA05846.1.
FSGV01000011 Genomic DNA. Translation: SIA26447.1.
FSLI01000007 Genomic DNA. Translation: SIG41543.1.
FSNK01000001 Genomic DNA. Translation: SIH93846.1.
FSQV01000004 Genomic DNA. Translation: SIN13504.1.
FVBY01000005 Genomic DNA. Translation: SKE73849.1.
FVIM01000004 Genomic DNA. Translation: SKN72915.1.
FVKM01000016 Genomic DNA. Translation: SKR44579.1.
FVPM01000010 Genomic DNA. Translation: SKX52008.1.
FVVB01000004 Genomic DNA. Translation: SLE53445.1.
FVWC01000062 Genomic DNA. Translation: SLG80931.1.
FWCV01000008 Genomic DNA. Translation: SLL32181.1.
RefSeqiWP_005110123.1. NZ_MLCG01000002.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1M8YN24_9MYCO
AccessioniPrimary (citable) accession number: A0A1M8YN24
Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2017
Last sequence update: March 15, 2017
Last modified: October 25, 2017
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported