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Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Bradyrhizobium erythrophlei
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotationSAAS annotation

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotationSAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationSAAS annotation, Transferase
Biological processCell cycle, Cell divisionUniRule annotationSAAS annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotationSAAS annotation (EC:2.4.1.227UniRule annotationSAAS annotation)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
Gene namesi
Name:murGUniRule annotation
ORF Names:SAMN05443248_6703Imported
OrganismiBradyrhizobium erythrophleiImported
Taxonomic identifieri1437360 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000189796 Componenti: Chromosome i

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 143Glyco_transf_28InterPro annotationAdd BLAST137
Domaini190 – 355Glyco_tran_28_CInterPro annotationAdd BLAST166

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit
TIGRFAMsiTIGR01133 murG, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1M5WP25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTQPLILLA AGGTGGHLFP AEALGVELIR RGLRVRLATD SRALRYSGLF
60 70 80 90 100
SKDTIDVVPS ATVRGRTPWS LAATGAMLAA GTAVSLNLMR RLKPSAVVGF
110 120 130 140 150
GGYPTLPPLL AARMFGVPGI IHEANAVLGR ANRFLSSRVS AIATSLPGVL
160 170 180 190 200
DRDPALSGKT TTVGTPMRPA ILAAAAVKFV TPEAAGPFRL LVVGGSQGAR
210 220 230 240 250
VMADIVPSAI ERLEPALWNR LVLTQQVREE DMARVRVVYD RLKINAELAP
260 270 280 290 300
FFGDLPARLA SSQLVISRSG AGTVAELGAI GRPSILVPLP GSIDQDQFAN
310 320 330 340 350
AGVLAQAGGA LRIAQADFTP DRLAAEISAL AAEPARLTAM AAGARTVGRL
360
DAAERLADLV MKVAGI
Length:366
Mass (Da):38,008
Last modified:March 15, 2017 - v1
Checksum:iE688BEA18352101C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LT670817 Genomic DNA Translation: SHH89219.1

Similar proteinsi

Entry informationi

Entry nameiA0A1M5WP25_9BRAD
AccessioniPrimary (citable) accession number: A0A1M5WP25
Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2017
Last sequence update: March 15, 2017
Last modified: September 27, 2017
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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