Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Xylella fastidiosa
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotationSAAS annotation

Catalytic activityi

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotationSAAS annotation

Pathwayi: 7,8-dihydroneopterin triphosphate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes 7,8-dihydroneopterin triphosphate from GTP.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. GTP cyclohydrolase FolE2 (folE2), GTP cyclohydrolase 1 (folE), GTP cyclohydrolase FolE2 (folE2), GTP cyclohydrolase FolE2 (folE2), GTP cyclohydrolase 1 (folE), GTP cyclohydrolase 1 (folE)
This subpathway is part of the pathway 7,8-dihydroneopterin triphosphate biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 7,8-dihydroneopterin triphosphate from GTP, the pathway 7,8-dihydroneopterin triphosphate biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei155May be catalytically importantUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

UniPathwayiUPA00848; UER00151.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
Gene namesi
Name:folE2UniRule annotation
ORF Names:XFHB_04755Imported
OrganismiXylella fastidiosaImported
Taxonomic identifieri2371 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
Proteomesi
  • UP000196980 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the GTP cyclohydrolase IV family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK09007.

Family and domain databases

HAMAPiMF_01527_B. GTP_cyclohydrol_B. 1 hit.
InterProiView protein in InterPro
IPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
PANTHERiPTHR36445. PTHR36445. 1 hit.
PfamiView protein in Pfam
PF02649. GCHY-1. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1L2AF30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTSIPDVAV HDSPAVAAPL RWVGMDGIVV PVQLTTADGG QHVIGRARAQ
60 70 80 90 100
IDLPAMEVKG IHMSRLYRLL DTHAVEPLTP VGICGLLSAM VNSHADCAST
110 120 130 140 150
AARVDWHFDW LRRVPALVSN DLSGWRGYPV SLRAEYSAVH VQFWLCVEVG
160 170 180 190 200
YSSTCPCSAA LARQMLADAF LQEHVEVSAL SPETVADWLR SNGSYATPHS
210 220 230 240 250
QRSVARIEVA LTEQAVELGL PALVDCAERI LSTPVQAAVR RVDEQAFARL
260 270 280 290
NGANLMYVED ATRRLQHGLA IHYSAFRVHV RHLESLHPHD AVASTADE
Length:298
Mass (Da):32,460
Last modified:March 15, 2017 - v1
Checksum:i5B05FD2BBC7C9299
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009885 Genomic DNA. Translation: ALR07694.1.

Genome annotation databases

KEGGixfh:XFHB_04755.

Similar proteinsi

Entry informationi

Entry nameiA0A1L2AF30_XYLFS
AccessioniPrimary (citable) accession number: A0A1L2AF30
Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2017
Last sequence update: March 15, 2017
Last modified: December 20, 2017
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported