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Protein
Submitted name:

Thrombomodulin

Gene

THBD

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
ThrombomodulinImported
Gene namesi
Name:THBDImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei493 – 516HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500968191923 – 549Sequence analysisAdd BLAST527

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 149C-type lectinInterPro annotationAdd BLAST113
Domaini303 – 341EGF-likeInterPro annotationAdd BLAST39
Domaini342 – 381EGF-likeInterPro annotationAdd BLAST40
Domaini420 – 457EGF-likeInterPro annotationAdd BLAST38

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00810000125382.
OMAiLCGPLCV.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link_sf.
IPR016187. CTDL_fold.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_cys_sf.
IPR015149. Tme5_EGF-like.
PfamiView protein in Pfam
PF07645. EGF_CA. 2 hits.
PF00059. Lectin_C. 1 hit.
PF09064. Tme5_EGF_like. 1 hit.
SMARTiView protein in SMART
SM00034. CLECT. 1 hit.
SM00181. EGF. 6 hits.
SM00179. EGF_CA. 4 hits.
SUPFAMiSSF56436. SSF56436. 1 hit.
SSF57184. SSF57184. 2 hits.
PROSITEiView protein in PROSITE
PS00010. ASX_HYDROXYL. 3 hits.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 2 hits.

Sequencei

Sequence statusi: Complete.

A0A1L1RWW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRLLLPLLL AGLGLGLGLV LGLGEPEPPA PSGAQCLEHD CFAVFWTPGP
60 70 80 90 100
FAAASAACER HGGHLMTVRS TVAEDAIELL LRKRGGRLWL GLRLPTLCTE
110 120 130 140 150
PARRLRGFQW VTGDTGTDYD NWVPSGRRCG QLCVTVSREL SWEERRCDEP
160 170 180 190 200
ADGFLCEYNY PDSCPRLSPS DGASLTYRTP FGAAGGDFLA LPHGSTAFVS
210 220 230 240 250
PMGLQLLCEA AADSGKMRWG RSEPGAWPCR LDNGGCEGSC EELDGTPSCA
260 270 280 290 300
CPAGKKLGPD GRSCVSPCAG APCEQHCVPD GEGFHCMCSE GYELGPDGSS
310 320 330 340 350
CQDVDDCVKV PEVCEQVCYN TEGGFECHCH RGYEMVEGHC KPISSCSTGP
360 370 380 390 400
CDHTCEDVPG GYQCSCYNGY VVNPKNPTEC LQKCEDGRCL AECDASGLYC
410 420 430 440 450
VCPEGFLLDH LPNGVSLCVD IDECESNHCE HNCTNTAGSY ICHCQPGYMP
460 470 480 490 500
FDVNHCIPIS QEDNEDGYSG DSGPPWPVPS HIPPKAEHLH PGALVGITMG
510 520 530 540
VLCAALVLLA VGYHLARKRC HPPSSMEYKC GSPREKEMGL QQVSASQKV
Length:549
Mass (Da):58,868
Last modified:February 15, 2017 - v1
Checksum:i4B68B4DB3D20F598
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000266 Genomic DNA. No translation available.
RefSeqiXP_004940194.1. XM_004940137.2.

Genome annotation databases

EnsembliENSGALT00000086586; ENSGALP00000063331; ENSGALG00000044442.
GeneIDi101752029.

Similar proteinsi

Entry informationi

Entry nameiA0A1L1RWW5_CHICK
AccessioniPrimary (citable) accession number: A0A1L1RWW5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2017
Last sequence update: February 15, 2017
Last modified: November 22, 2017
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported