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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Pseudomonas sp. NFPP09
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotationSAAS annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotationSAAS annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI)
  4. Enolase (eno)
  5. Pyruvate kinase (SAMN03159479_03612), Pyruvate kinase (SAMN03159479_01644)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei36SubstrateUniRule annotation1
Binding sitei113SubstrateUniRule annotation1
Binding sitei146SubstrateUniRule annotation1
Binding sitei197ATPUniRule annotation1
Binding sitei314ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi340 – 343ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
Biological processGlycolysisUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotationSAAS annotation (EC:2.7.2.3UniRule annotationSAAS annotation)
Gene namesi
Name:pgkUniRule annotation
ORF Names:SAMN03159479_03933Imported
OrganismiPseudomonas sp. NFPP09Imported
Taxonomic identifieri1566211 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000183179 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Structurei

3D structure databases

SMRiA0A1K1ZXD8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni59 – 62Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.40.50.12603 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1K1ZXD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVLKMTDLD LQGKRVLIRE DLNVPVKDGV VTSDARILAS LPTIKLALEK
60 70 80 90 100
GAAVMVCSHL GRPTEGEFSA ENSLKPVADY LSRALGREVP LVADYLGGVE
110 120 130 140 150
VKAGDIVLFE NVRFNKGEKK NADELAQQYA ALCDVFVMDA FGTAHRAEGS
160 170 180 190 200
THGVAKFAKV AAAGPLLAAE LDALGKALGN PAKPMAAIVA GSKVSTKLDV
210 220 230 240 250
LNSLSQICDQ LIVGGGIANT FLAAAGHPVG KSLYEPDLLD TARAIAAKVS
260 270 280 290 300
VPLPVDVVVA KEFAESAAAT VKLIADVADD DMILDIGPQT AAQFAELLKS
310 320 330 340 350
SRTILWNGPV GVFEFDQFGN GTKVLAQAIA DSAAFSIAGG GDTLAAIDKY
360 370 380
GVAQQISYIS TGGGAFLEFV EGKVLPAVEV LEARAKA
Length:387
Mass (Da):40,187
Last modified:February 15, 2017 - v1
Checksum:i5B8FC09395950931
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FPJV01000005 Genomic DNA Translation: SFX78801.1
RefSeqiWP_011063958.1, NZ_FPJV01000005.1

Genome annotation databases

GeneIDi29824806

Similar proteinsi

Entry informationi

Entry nameiA0A1K1ZXD8_9PSED
AccessioniPrimary (citable) accession number: A0A1K1ZXD8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2017
Last sequence update: February 15, 2017
Last modified: March 28, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported