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Protein

Pyruvate kinase

Gene

A9486_15570

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 5 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk), Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA1), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA), 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI), 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno), Enolase (eno), Enolase (eno), Enolase (eno), Enolase (eno), Enolase (eno), Enolase (eno), Enolase (eno), Enolase (eno)
  5. Pyruvate kinase (pykA1), Pyruvate kinase (MCCC1A01412_07425), Pyruvate kinase (pyk), Pyruvate kinase (COJ30_11890), Pyruvate kinase (pyk2), Pyruvate kinase (COE56_07990), Pyruvate kinase (BVG01_09765), Pyruvate kinase (pyk), Pyruvate kinase (pyk), Pyruvate kinase (CN488_18960), Pyruvate kinase (CON16_24335), Pyruvate kinase (CN272_12880), Pyruvate kinase (pyk), Pyruvate kinase (pyk), Pyruvate kinase (pykA1), Pyruvate kinase (A9486_00415), Pyruvate kinase (CN907_26205), Pyruvate kinase (COK92_16395), Pyruvate kinase (pyk), Pyruvate kinase (CN286_13255), Pyruvate kinase (A9486_15570), Pyruvate kinase (CN504_15055), Pyruvate kinase (ABW01_15615), Pyruvate kinase (pyk), Pyruvate kinase (pyk)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processGlycolysisUniRule annotation
LigandMagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

UniPathwayiUPA00109; UER00188

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinaseUniRule annotation (EC:2.7.1.40UniRule annotation)
Gene namesi
ORF Names:A9486_15570Imported, BVG01_24145Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000181973 Componenti: Unassembled WGS sequence
  • UP000191148 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 342PKInterPro annotationAdd BLAST342
Domaini356 – 470PK_CInterPro annotationAdd BLAST115
Domaini504 – 575PEP-utilizersInterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the pyruvate kinase family.UniRule annotation

Family and domain databases

CDDicd00288 Pyruvate_Kinase, 1 hit
Gene3Di2.40.33.10, 1 hit
3.40.1380.20, 1 hit
InterProiView protein in InterPro
IPR008279 PEP-util_enz_mobile_dom
IPR036637 Phosphohistidine_dom_sf
IPR001697 Pyr_Knase
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
IPR011037 Pyrv_Knase-like_insert_dom_sf
IPR018209 Pyrv_Knase_AS
IPR015793 Pyrv_Knase_brl
IPR015795 Pyrv_Knase_C
IPR036918 Pyrv_Knase_C_sf
IPR015806 Pyrv_Knase_insert_dom_sf
PANTHERiPTHR11817 PTHR11817, 1 hit
PfamiView protein in Pfam
PF00391 PEP-utilizers, 1 hit
PF00224 PK, 1 hit
PF02887 PK_C, 1 hit
PRINTSiPR01050 PYRUVTKNASE
SUPFAMiSSF50800 SSF50800, 1 hit
SSF51621 SSF51621, 2 hits
SSF52009 SSF52009, 1 hit
SSF52935 SSF52935, 1 hit
TIGRFAMsiTIGR01064 pyruv_kin, 1 hit
PROSITEiView protein in PROSITE
PS00110 PYRUVATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1J9VED0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKTKIVCTI GPASESIEKL EQLIEAGMNV ARLNFSHGSH EEHGARIKNI
60 70 80 90 100
REASKKTGKT VGILLDTKGP EIRTHDFVDG QAELVTGAEV VLSTEQVLGT
110 120 130 140 150
AEKFSVSYAG LYDDVDPGSR ILIDDGLIEL EVIEKADGNI RTKVLNSGTV
160 170 180 190 200
KNKKGVNVPN VSIKLPGITE KDVKDIIFGI EQKVDFIAAS FVRKAADVLE
210 220 230 240 250
IRELLEEHNA QYIQIVPKIE NQEGIDNIDS ILEVSDGLMV ARGDMGVEIP
260 270 280 290 300
PEEVPLVQKR LIKKCNVLGK PVITATQMLD SMQRNPRPTR AEASDVANAI
310 320 330 340 350
FDGTDAIMLS GETAAGQYPV EAVTMMANIA VRVEKSLQYE DMFKKRIKEF
360 370 380 390 400
TPTITDAISQ SVAHTALALD VAAIVAPTES GYTAKMISKY RPKSPIVAVT
410 420 430 440 450
SDEQVGRRLA LVWGVQAFMA EKRAASTDEM LDTAIQTGMD AGLIGLGDTV
460 470 480 490 500
VITAGVPVAE TGTTNLMKIH VVGEEVAKGQ GIGRKAAKGK VVVAKTAAEA
510 520 530 540 550
VANVNEGDIL VTTSTDKDMI PAIEKAAALV VEEGGLTSHA AVVGVSIGIP
560 570 580
VIVGVNGVTT TLKNGQEVTV DAARGIVYNG HAEVL
Length:585
Mass (Da):62,268
Last modified:February 15, 2017 - v1
Checksum:iE6669BDA722F7D0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LZQX01000043 Genomic DNA Translation: OJD89496.1
MTAU01000021 Genomic DNA Translation: OPD56493.1
RefSeqiWP_001232665.1, NZ_MTAU01000021.1

Similar proteinsi

Entry informationi

Entry nameiA0A1J9VED0_BACAN
AccessioniPrimary (citable) accession number: A0A1J9VED0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2017
Last sequence update: February 15, 2017
Last modified: February 28, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health