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Protein

DEAD-box ATP-dependent RNA helicase CshA

Gene

cshA

Organism
Bacillus sp. FMQ74
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.Curated

Catalytic activityi

ATP + H2O = ADP + phosphate.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicase0 PublicationCurated, Hydrolase, RNA-bindingCurated
Biological processStress responseCurated
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DEAD-box ATP-dependent RNA helicase CshACurated (EC:3.6.4.13Curated)
Gene namesi
Name:cshACurated
ORF Names:BLL41_142800 Publication
OrganismiBacillus sp. FMQ740 Publication
Taxonomic identifieri1913579 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000181920 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm Curated

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmCurated

Interactioni

Subunit structurei

Oligomerizes, may be a member of the RNA degradosome.Curated

Structurei

3D structure databases

SMRiA0A1J5X6U4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 31Q_MOTIFImportedAdd BLAST29
Domaini34 – 204Helicase ATP-bindingImportedAdd BLAST171
Domaini215 – 375Helicase C-terminalImportedAdd BLAST161

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi3 – 31Q motifCuratedAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family. CshA subfamily.Curated

Family and domain databases

CDDicd00079. HELICc. 1 hit.
HAMAPiMF_01493. DEAD_helicase_CshA. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR030880. DEAD_helicase_CshA.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1J5X6U4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTITFQDFNL SSDLMKAINR MGFEEATPIQ AQTIPLGLSN KDVIGQAQTG
60 70 80 90 100
TGKTAAFGIP LVEKINPESP NIQAIVIAPT RELAIQVSEE LYKIGQDKRA
110 120 130 140 150
KVLPIYGGQD IGRQIRALKK NPNIIVGTPG RLLDHINRRT IRLNNVNTVV
160 170 180 190 200
MDEADEMLNM GFIDDIESIL SNVPSEHQTL LFSATMPAPI KRIAERFMTE
210 220 230 240 250
PEHVKVKAKE MTVSNIQQFY LEVQERKKFD TLTRLLDIQS PELAIVFGRT
260 270 280 290 300
KRRVDELAEA LNLRGYAAEG IHGDLTQAKR MVALRKFKEG AIEVLVATDV
310 320 330 340 350
AARGLDISGV THVYNFDVPQ DPESYVHRIG RTGRAGKTGM AMTFITPREK
360 370 380 390 400
SMLRAIEQTT KRKMDRMKEP TLDEALEGQQ QVTVERLRTT ISENNLNFYM
410 420 430 440 450
TAAAELLEDH DAVTVVAAAI KMATKEPDDT PVRLTDEAPM VSKRYKNQRS
460 470 480 490
SKRRDGQGGG YRGGKGKSNN RSSYDKKRSN DRRSSGDRRQ KKSY
Length:494
Mass (Da):55,330
Last modified:February 15, 2017 - v1
Checksum:iA44C5EAE314E46ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MOEO01000007 Genomic DNA. Translation: OIR60585.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1J5X6U4_9BACI
AccessioniPrimary (citable) accession number: A0A1J5X6U4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2017
Last sequence update: February 15, 2017
Last modified: October 25, 2017
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.0 Publication

Keywords - Technical termi

Complete proteome0 Publication