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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Halomicrobium zhouii
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei185GTPUniRule annotation1
Binding sitei189GTPUniRule annotation1
Binding sitei232GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi66 – 70GTPUniRule annotation5
Nucleotide bindingi154 – 156GTPUniRule annotation3

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
ORF Names:SAMN05216559_2394Imported
OrganismiHalomicrobium zhouiiImported
Taxonomic identifieri767519 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHaloarculaceaeHalomicrobium
Proteomesi
  • UP000199062 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 250TubulinInterPro annotationAdd BLAST193
Domaini252 – 369Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR018247. EF_Hand_1_Ca_BS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 1 hit.
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1I6LB46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSIIDDAIE EAEDEREEPT SGGDRDAANT PETTDDMNTS GTMTDDELSS
60 70 80 90 100
VVKDLETKIT VVGCGGAGGN TVTRMMEEGI HGAKLVAANT DAQHLADEVM
110 120 130 140 150
ADTKILIGRK RTGGRGAGSV PKIGEEAAQE NIEDIQQSIS GSDMVFVTAG
160 170 180 190 200
LGGGTGTGSA PVVAQAAQEA GALTISIVTI PFTAEGERRR ANADAGLERL
210 220 230 240 250
RSVSDTVIVV PNDRLLDYAP SMPLQDAFKI CDRVLMRSVK GMTELITKPG
260 270 280 290 300
LVNVDFADVR TIMENGGVAM IGLGESDSEN KAQDSIRSAL RSPLLDVEFD
310 320 330 340 350
GANSALVNVV GGPDMSIEEA EGVVEEIYDR IDPDARIIWG ASVNDDFEGK
360 370 380
METMIVVTGV ESPQIYGKSE AEREKAAKQV GEDIDYVE
Length:388
Mass (Da):41,002
Last modified:November 22, 2017 - v1
Checksum:iBCA0E95977C61FED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FOZK01000002 Genomic DNA. Translation: SFS00696.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1I6LB46_9EURY
AccessioniPrimary (citable) accession number: A0A1I6LB46
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: December 20, 2017
This is version 2 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported