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Protein

Alanine racemase

Gene

SAMN04488082_11518

Organism
Desulfomicrobium apsheronum
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (SAMN04488082_11518)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei36Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei135SubstrateUniRule annotation1
Active sitei267Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei315Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotation
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
ORF Names:SAMN04488082_11518Imported
OrganismiDesulfomicrobium apsheronumImported
Taxonomic identifieri52560 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfomicrobiaceaeDesulfomicrobium
Proteomesi
  • UP000198635 Componenti: Unassembled WGS sequence

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei36N6-(pyridoxal phosphate)lysineUniRule annotation1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini246 – 373Ala_racemase_CInterPro annotationAdd BLAST128

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di2.40.37.10, 1 hit
3.20.20.10, 1 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1I3X4L9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIWYNHVRT HIRLQALVDN YRLIRTRATD PAPVIKSDAY GHGLPEAAGA
60 70 80 90 100
LFAAGARTMA AGTVGEAAVL KDTVPEAEVI SLLGPLDAED YACVCERDIV
110 120 130 140 150
AFVGSTEQLL LLEEAASHAG TTVRVALKFD TGMARLGFAP DEAAGVADTL
160 170 180 190 200
DGLEHVRATM ACSHLATADD PGQVEYVREQ GDRFARILKT LHARGLDVRA
210 220 230 240 250
SLANSGAIFG HPDLHHDLQR PGIALYGGNP FHGTPWEEKG LGLKPTMQVS
260 270 280 290 300
SRLMQIRTIP AGQSVSYGRT FTAPAEIRVG IVAVGYADNY SRGLSGKARM
310 320 330 340 350
LLHGKRVPVL GRVCMQLTAV DLTGVPEAAA GDEIFMLGGE GPFAISADEL
360 370
AGWWGTITYE VFCLLGQNPR EYVE
Length:374
Mass (Da):40,017
Last modified:November 22, 2017 - v1
Checksum:i5A9058F37D1457BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FORX01000015 Genomic DNA Translation: SFK13791.1

Similar proteinsi

Entry informationi

Entry nameiA0A1I3X4L9_9DELT
AccessioniPrimary (citable) accession number: A0A1I3X4L9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: January 31, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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