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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Thiohalospira halophila DSM 15071
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi490MagnesiumUniRule annotation1
Metal bindingi496MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotation, RNA-bindingUniRule annotation, Transferase
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
ORF Names:SAMN05660831_02431Imported
OrganismiThiohalospira halophila DSM 15071Imported
Taxonomic identifieri1123397 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeThiohalospira
Proteomesi
  • UP000198611 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini626 – 694S1 motifInterPro annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili599 – 622Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 2 hits
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1I1VPV6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEAPQSVRR EIRYGDHDLV LETGEVARQA DGAVMVSMGD TVVLVTAVGR
60 70 80 90 100
PEADPGRDFF PLTVNYQERT YAAGRIPGGF FRREGRPSEK ETLTSRLIDR
110 120 130 140 150
PIRPLFPDGF THEVQVIATV ISLDPEVDPD IPSLIGASAA LALSGLPFQG
160 170 180 190 200
PIGAARVGYS NGEYQLNPAF SALEESDLDL VVAGTDSAVL MVESEASELS
210 220 230 240 250
EETMLGAVMF GHRAMQPVIE AIRELAAEAG RPAWDWQPAE RDTDLDRAVA
260 270 280 290 300
SAAEARLAEA YGLADKQERS ARLREVRAAV VDELAGDGDE GHEAGAVKEA
310 320 330 340 350
LGALEKRLVR GRILAGEPRI DGRDLTGVRP ITIRTGLLPR THGSALFTRG
360 370 380 390 400
ETQAMVVTTL GTSRDAQTID ALEGKYEDNF MLHYNFPPYC VGETGFVGSP
410 420 430 440 450
KRREIGHGRL ARRGVSAVLP KQDDFPYSIR VVSEITESNG SSSMASVCGT
460 470 480 490 500
SLSLMDAGVP VKAPVAGIAM GLIKEGEDHA VISDILGDED HLGDMDFKVA
510 520 530 540 550
GTNEGVTALQ MDIKIDGITE AIMESALEQA RSGRLHILGE MNAVLAAPRQ
560 570 580 590 600
DMSSHAPRYI TMHINPARIR DVIGKGGSVI RGITEETGAN VEVDDDGTVR
610 620 630 640 650
IASTERDAAE EARRRIEELT AEVEVGKVYE GRVAKIMDFG AFVTILPGRD
660 670 680 690
GLVHISQISD ERVQDVNDKL SEGENVQVKV LEVDNQGRIR LSMKAVGKE
Length:699
Mass (Da):75,304
Last modified:November 22, 2017 - v1
Checksum:iC4CA02627502F4F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FOMJ01000010 Genomic DNA Translation: SFD84875.1

Similar proteinsi

Entry informationi

Entry nameiA0A1I1VPV6_9GAMM
AccessioniPrimary (citable) accession number: A0A1I1VPV6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: February 28, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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