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Protein

Protein translocase subunit SecA

Gene

secA

Organism
Pseudomonas indica
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.UniRule annotation

Cofactori

Zn2+SAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi126 – 133ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, TranslocationUniRule annotationSAAS annotation, Transport
LigandATP-bindingUniRule annotationSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding, ZincSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecAUniRule annotation
Gene namesi
Name:secAUniRule annotation
ORF Names:SAMN05216186_11148Imported
OrganismiPseudomonas indicaImported
Taxonomic identifieri137658 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000198706 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation
  • Cytoplasm UniRule annotationSAAS annotation
  • Note: Distribution is 50-50.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, CytoplasmUniRule annotationSAAS annotation, Membrane

Interactioni

Subunit structurei

Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 643SECA_MOTOR_DEADInterPro annotationAdd BLAST617

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili38 – 65Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the SecA family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

HAMAPiMF_01382 SecA, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR004027 SEC_C_motif
IPR000185 SecA
IPR020937 SecA_CS
IPR011115 SecA_DEAD
IPR014018 SecA_motor_DEAD
IPR011130 SecA_preprotein_X-link_dom
IPR011116 SecA_Wing/Scaffold
IPR036266 SecA_Wing/Scaffold_sf
IPR036670 SecA_X-link_sf
PANTHERiPTHR30612 PTHR30612, 1 hit
PfamiView protein in Pfam
PF02810 SEC-C, 1 hit
PF07517 SecA_DEAD, 1 hit
PF01043 SecA_PP_bind, 1 hit
PF07516 SecA_SW, 1 hit
PRINTSiPR00906 SECA
SMARTiView protein in SMART
SM00957 SecA_DEAD, 1 hit
SM00958 SecA_PP_bind, 1 hit
SUPFAMiSSF52540 SSF52540, 3 hits
SSF81767 SSF81767, 1 hit
SSF81886 SSF81886, 2 hits
TIGRFAMsiTIGR00963 secA, 1 hit
PROSITEiView protein in PROSITE
PS01312 SECA, 1 hit
PS51196 SECA_MOTOR_DEAD, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1G9F9Q9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPLHAAVAA RGRASIPRME VFADMFAPLL KKLFGSKNER EVKRMLKAVQ
60 70 80 90 100
AINALEQQML ALSDEQLRAK TVEFKARLAK GETLDQVLPE AFAVAREAGK
110 120 130 140 150
RVMGMRHFDV QLIGGMTLHE GKIAEMRTGE GKTLVATLAV YLNALEGKGV
160 170 180 190 200
HVVTVNDYLA RRDANWMRPL YEFLGLSVGI VTPFQPPEEK RAAYAADITY
210 220 230 240 250
GTNNELGFDY LRDNMAFSLE DKFQRELNFA VIDEVDSILI DEARTPLIIS
260 270 280 290 300
GQAEDSSKLY QQINQLIPRL KQHIEEEEGV VTQEGHFSVD EKTRQVELNE
310 320 330 340 350
QGHQFIEEML TQAGLLAEGE SLYSAHNLSL LTHVYAGLRA HKLFHRNIEY
360 370 380 390 400
IVQNNQVLLI DEHTGRTMPG RRLSEGLHQA IEAKEGLPIQ AESQTLASTT
410 420 430 440 450
FQNYFRLYKK LAGMTGTADT EAFEFHQIYG LDVVVIPTNK PLARKDFNDL
460 470 480 490 500
VYLTQEEKYA AIITDIKECQ ANGRPVLVGT ASIESSEYVS QLLQKEGIEH
510 520 530 540 550
KVLNAKFHDK EAEIIAQAGR PGAVTIATNM AGRGTDILLG GNWEAEVAVL
560 570 580 590 600
ESPSEEQIAQ IKADWQKRHQ QVIEAGGLHV IASERHESRR IDNQLRGRAG
610 620 630 640 650
RQGDPGSSRF YLSLEDNLMR IFASDRVKNF MKALGMQSGE AIEHRMVTNA
660 670 680 690 700
IEKAQRKVEG RNFDMRKQLL EFDDVANEQR KVIYHMRNSL LAATDVGETI
710 720 730 740 750
AEFREEVLTN AINQHIPPQS LPEQWDIGGL EAALRSDFGI DLPIQQWLDE
760 770 780 790 800
DEKLYEETLR ERILQALLDA YKEKEDLAGA EALRTFEKQI LLRVLDDLWK
810 820 830 840 850
DHLSTMDHLR YGIHLRGYAQ KNPKQEYKRE SFNLFQDLLD SIKRDTIRVL
860 870 880 890 900
SHVQVRREDP AEEEARLRRE AEALAQRMQF QHAEASALQP PPEPQGEAEE
910 920 930
GGAAVAQMPV RQEQKIGRNE PCPCGSGKKY KHCHGQVN
Length:938
Mass (Da):105,995
Last modified:November 22, 2017 - v1
Checksum:iFE66455A6A2327DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FNFD01000011 Genomic DNA Translation: SDK85147.1

Similar proteinsi

Entry informationi

Entry nameiA0A1G9F9Q9_9PSED
AccessioniPrimary (citable) accession number: A0A1G9F9Q9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: April 25, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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