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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Photorhabdus luminescens (Xenorhabdus luminescens)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotationSAAS annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotationSAAS annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate, the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseImported, LigaseUniRule annotationSAAS annotation, Transferase
Biological processPyridine nucleotide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotationSAAS annotation (EC:6.3.4.21UniRule annotationSAAS annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
ORF Names:SAMN02982990_01289Imported
OrganismiPhotorhabdus luminescens (Xenorhabdus luminescens)Imported
Taxonomic identifieri29488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesMorganellaceaePhotorhabdus
Proteomesi
  • UP000183223 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_00570. NAPRTase. 1 hit.
InterProiView protein in InterPro
IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR036068. Nicotinate_pribotase_like_C.
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiView protein in Pfam
PF04095. NAPRTase. 1 hit.
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1G5QAG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLDATPIIK SLLDTDAYKL HMQQAVYHRY SHMPVVAEFR CRGDELLGEY
60 70 80 90 100
AAELRYQVNM MANLALTDAE FNYLSSLPFF KADYLDWLKT FRFNPQQVNI
110 120 130 140 150
SVTDGGQLAI RISGLWHEVI MWEVPLLALI SELVHRYRSP DNAVENAVNQ
160 170 180 190 200
LRKLIKLFYQ KAESEGIDLS SFKLMDFGTR RRFSHCVQHA IVSELQQHFP
210 220 230 240 250
YLIGTSNYQL AQQLGLPPVG TQAHEWFQAH QQISPDLASS QREALQSWLK
260 270 280 290 300
EYPNQLGIAL TDCITMDAFL RDFDAQFAKS YQGLRHDSGD PVQWGEKAIA
310 320 330 340 350
HYQKLGIDPM TKTLVFSDSL DFQKALTLYR HFHNRINLIF GIGTQLTCNI
360 370 380 390 400
PGVNPLNIVI KLVECNGKPV AKLSDSPGKT ICEDNEFVNR LRAAFDIPQA

KQAC
Length:404
Mass (Da):46,044
Last modified:April 12, 2017 - v1
Checksum:i8700A8E5A9723D8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FMWJ01000004 Genomic DNA. Translation: SCZ58566.1.
RefSeqiWP_049585332.1. NZ_FMWJ01000004.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1G5QAG9_PHOLU
AccessioniPrimary (citable) accession number: A0A1G5QAG9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: October 25, 2017
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported