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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methylophilales bacterium RIFCSPHIGHO2_02_FULL_57_10
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:A3B82_04265Imported
OrganismiMethylophilales bacterium RIFCSPHIGHO2_02_FULL_57_10Imported
Taxonomic identifieri1801614 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadales

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 86Arg_tRNA_synt_NInterPro annotationAdd BLAST84
Domaini435 – 552DALR_1InterPro annotationAdd BLAST118

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1G1AQM3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSHLTELLA QAAKAVAPDL QNVSILIERP KTAQHGDFAT NLAMLLAKSL
60 70 80 90 100
KQNPRAIAEA LIKALPPSQY VAKAEIAGAG FINFFVTAKA RTTTIRQVFA
110 120 130 140 150
EGTGFGLSTM GKGRKVMVEF VSANPTGPLH IGHGRGAAVG DCLCRLLQAT
160 170 180 190 200
GWTVTREFYY NDAGAQINNL ILSVQCRCKG LTPDDPAWPE DGYRGDYITD
210 220 230 240 250
IAHAYLARET VEADGRHVTA SGDPEDAAAI HQFAIAYLRH EQDSDLHAFG
260 270 280 290 300
VYFDVFSLES ALYTDGKVEE VVSRLIAGGH TYVQDDALWL RTTSFGDDKD
310 320 330 340 350
RVMRKREGGY TYFVPDIAYH VDKWSRGFER VINEQGADHH STITRVRAGL
360 370 380 390 400
QALDIGIPQG WPEYVLHQMV TVMRSGEEMK ISKRAGSYVT LRDLIDEVGC
410 420 430 440 450
DATRYFLTAR RADSQLVFDI DLARAQTVDN PVYYIQYAHA RICSVLEQWG
460 470 480 490 500
GDVAALQDAE LDPLSTEHEL ALLQRLAEFP EVVENAAREL APHIVAYYLK
510 520 530 540 550
DLAGDLHSYY NAQQFLVENE KVKLARLALI TATRQVLRTG LNLLGVSAPE

TM
Length:552
Mass (Da):61,047
Last modified:February 15, 2017 - v1
Checksum:i50C71FEEE0A05005
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MHBT01000070 Genomic DNA Translation: OGV72760.1

Similar proteinsi

Entry informationi

Entry nameiA0A1G1AQM3_9PROT
AccessioniPrimary (citable) accession number: A0A1G1AQM3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2017
Last sequence update: February 15, 2017
Last modified: April 25, 2018
This is version 12 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health