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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Dietzia sp. HMSC21D01
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei384UniRule annotation1
Active sitei514UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
ORF Names:HMPREF3086_16660Imported
OrganismiDietzia sp. HMSC21D01Imported
Taxonomic identifieri1581054 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesDietziaceaeDietzia
Proteomesi
  • UP000176795 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd05015. SIS_PGI_1. 1 hit.
cd05016. SIS_PGI_2. 1 hit.
Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase. 1 hit.
InterProiView protein in InterPro
IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
IPR035476. SIS_PGI_1.
IPR035482. SIS_PGI_2.
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiView protein in Pfam
PF00342. PGI. 1 hit.
PRINTSiPR00662. G6PISOMERASE.
PROSITEiView protein in PROSITE
PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1F1KDC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDISTTEQW AAVEGLVPSI GEVTLRELFD ADPERGRRMS VTAGDLHVDL
60 70 80 90 100
SKHLVTDEIL HALTELAHAA RLPAQRAAMF RGDRINTTED RSVLHTALRL
110 120 130 140 150
PADAELVVDG SDVVADVHAV LARMTDLADR VRSGEWTGYT GERIDTVVNI
160 170 180 190 200
GIGGSDLGPV MVDAALRDLQ TAGIRARYVS NVDPADLTAT LAEINPATTL
210 220 230 240 250
VVVASKTFTT QETMANAHAA RRHFIEALRS EDAIASHFVA VSTAADKVAD
260 270 280 290 300
FGIAPDNMFG FWDWVGGRYS VSSAIGLSVM ITAGPAAFVE MLEGFHTMDL
310 320 330 340 350
HFATEAPEHN APVLMALLGI WYTCFLGAQS KAVIPYSQDL HRFPAYLQQL
360 370 380 390 400
TMESLGKSVR LDGSDVTYPT GEVYWGEPGT NGQHAFFQLL HQGTQLVPVD
410 420 430 440 450
FIGVARPAAD LAADVPGSAE PVSMHDMLMA NLFAQSRVLA FGKTEEEVLA
460 470 480 490 500
DGVDPALAPH KVMPGNRPST TILAPSLSPS VVGQLIALYE HIVFTQAAIL
510 520 530 540 550
GINAFDQWGV ELGKAQAGEL LSALTAETHP EPGFDSSTDS LVEIYREARG

RR
Length:552
Mass (Da):59,326
Last modified:February 15, 2017 - v1
Checksum:i5C9403C5CB5F74DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LWPP01000596 Genomic DNA. Translation: OFS13538.1.
RefSeqiWP_061229063.1. NZ_KV824137.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1F1KDC0_9ACTN
AccessioniPrimary (citable) accession number: A0A1F1KDC0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2017
Last sequence update: February 15, 2017
Last modified: September 27, 2017
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported