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Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

BAE44_0022829

Organism
Dichanthelium oligosanthes
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N7-methylguanine(46) in tRNA.UniRule annotationSAAS annotation

Pathwayi: N(7)-methylguanine-tRNA biosynthesis

This protein is involved in the pathway N(7)-methylguanine-tRNA biosynthesis, which is part of tRNA modification.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway N(7)-methylguanine-tRNA biosynthesis and in tRNA modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei83S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Binding sitei159S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Active sitei162UniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseUniRule annotationSAAS annotationImported, RNA-binding, Transferase, tRNA-bindingUniRule annotationSAAS annotation
Biological processtRNA processingUniRule annotationSAAS annotation
LigandS-adenosyl-L-methionineUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
Gene namesi
ORF Names:BAE44_0022829Imported
OrganismiDichanthelium oligosanthesImported
Taxonomic identifieri888268 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaePanicodaePaniceaeDichantheliinaeDichanthelium
Proteomesi
  • UP000095767 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni106 – 107S-adenosyl-L-methionine bindingUniRule annotation2
Regioni139 – 140S-adenosyl-L-methionine bindingUniRule annotation2
Regioni237 – 239S-adenosyl-L-methionine bindingUniRule annotation3

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_03055. tRNA_methyltr_TrmB_euk. 1 hit.
InterProiView protein in InterPro
IPR029063. SAM-dependent_MTases.
IPR025763. Trm8_euk.
IPR003358. tRNA_(Gua-N-7)_MeTrfase_Trmb.
PANTHERiPTHR23417. PTHR23417. 1 hit.
PTHR23417:SF16. PTHR23417:SF16. 1 hit.
PfamiView protein in Pfam
PF02390. Methyltransf_4. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiView protein in PROSITE
PS51625. SAM_MT_TRMB. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1E5UTK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRTNGANGG GDGQQQASAA GKLPRKRFYR ARAHSNPLSD SHFPVPVSPD
60 70 80 90 100
EVDLSQHYPR YFPADKGGEG EEPPPRIRFA DVGCGFGGLL VGLSPLFPDT
110 120 130 140 150
LMIGMELRDK VTEYVKERIL ALRASNPGHY DNISVVRTNS MKYIPNYFRK
160 170 180 190 200
AQITKMFFLF PDPHFKEKNH RRRVISMQLL DEYAYVMEVG GIIYTITDVE
210 220 230 240 250
ELGEWMRSCL EKHPLFEAIL EEEINADPVV KLLSTATEES QKVARNGGQT
260
FHAIFRRISL QEE
Length:263
Mass (Da):29,790
Last modified:January 18, 2017 - v1
Checksum:i1F08FE93A8262B7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LWDX02063880 Genomic DNA. Translation: OEL16154.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1E5UTK3_9POAL
AccessioniPrimary (citable) accession number: A0A1E5UTK3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: October 25, 2017
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported