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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Staphylococcus equorum
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi490MagnesiumUniRule annotation1
Metal bindingi496MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotation, RNA-bindingUniRule annotation, Transferase
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
ORF Names:AST02_04590Imported
OrganismiStaphylococcus equorumImported
Taxonomic identifieri246432 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000095586 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini626 – 699S1 motifInterPro annotationAdd BLAST74

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase. 1 hit.
InterProiView protein in InterPro
IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
IPR003029. S1_domain.
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiView protein in Pfam
PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiView protein in SMART
SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
SUPFAMiSSF46915. SSF46915. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiView protein in PROSITE
PS50126. S1. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1E5TU33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQEKKVFKT EWANRSLTIE TGQLAKQANG AVLVRYGDTV VLSTAVASKE
60 70 80 90 100
PRDVDFFPLM VNYEEKMYAA GKIPGGFKKR EGRPSDEATL TARLIDRPIR
110 120 130 140 150
PLFPKGYKHD VQIMNTVLSA DPDCSPEMAA MIGSSMALSV SDIPFQGPIA
160 170 180 190 200
GVNVGYVDGE YVINPTVAQK EVSRLDLEVA GHKDAVNMVE AGASEITESE
210 220 230 240 250
MLEGIFFGHN EIQRLVNFQQ EIVDHIQPVK TPFTPVEQDE TLAEKVKQLT
260 270 280 290 300
EANGLKEAVL TFDKQQRDIN LDTLKEKVVS EFIDEEDVNN AALIKDVHGI
310 320 330 340 350
LNSLVKEEVR RLIAEEKIRP DGRKSDEIRP LESEVGVLPR VHGSGLFTRG
360 370 380 390 400
QTQALSVLTL GSMSEYQILD GLGEEQQKRF MHHYNFPNYS VGETGPVRSP
410 420 430 440 450
GRREIGHGAL GERALSHVIP DTKDFPYTVR IVSEVLESNG SSSQASICGS
460 470 480 490 500
TLALMDAGVP IKAPVAGIAM GLVTRDDSYT ILTDIQGMED ALGDMDFKVA
510 520 530 540 550
GTSEGITAIQ MDIKIDGLTK EIIREALDQA REGRLAILDH MLQTIDTTRG
560 570 580 590 600
ELSAFAPKVV TMTIKPEKIR DVIGPGGKKI NEIIDQTGVK LDIEQDGTIF
610 620 630 640 650
IGAVDKDAIA EARSIIEDIT REAEVGQVYE GKVKRIEKYG AFVELFPGKD
660 670 680 690
ALVHISQIAN ERIDKVEDVL KIGDTFKIKV TEIDKQGRVN ASHKVLLSN
Length:699
Mass (Da):76,759
Last modified:January 18, 2017 - v1
Checksum:i6CE2C44ED249379F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LNNB01000009 Genomic DNA. Translation: OEK70738.1.
RefSeqiWP_069816004.1. NZ_LNNB01000009.1.

Genome annotation databases

EnsemblBacteriaiOEK70738; OEK70738; AST02_04590.

Similar proteinsi

Entry informationi

Entry nameiA0A1E5TU33_9STAP
AccessioniPrimary (citable) accession number: A0A1E5TU33
Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: September 27, 2017
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported