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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycobacterium holsaticum
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei387UniRule annotation1
Active sitei513UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
ORF Names:BHQ17_15625Imported
OrganismiMycobacterium holsaticumImported
Taxonomic identifieri152142 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000094243 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd05015. SIS_PGI_1. 1 hit.
cd05016. SIS_PGI_2. 1 hit.
Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase. 1 hit.
InterProiView protein in InterPro
IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
IPR035476. SIS_PGI_1.
IPR035482. SIS_PGI_2.
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiView protein in Pfam
PF00342. PGI. 1 hit.
PRINTSiPR00662. G6PISOMERASE.
PROSITEiView protein in PROSITE
PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1E3RSL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSADIPDITG TTAWQALQRH HDAIGETHLR QFFADDSARG TELTLTVGDL
60 70 80 90 100
YVDYSKHRLT RETLQLLVNL ARAAGLEQRR DAMFSGVHIN TSENRAVLHT
110 120 130 140 150
ALRLPRDAEL VVDGQNVVED VHAVLDRMGD FTDRLRSGEW TGATGERITT
160 170 180 190 200
VVNIGIGGSD LGPVMVYQAL RHYADAGISA RFVSNVDPAD LVATLHGLDP
210 220 230 240 250
ATTLFIVASK TFSTLETLTN ATAARRWLID GLGDAAVAKH FVAVSTNKKL
260 270 280 290 300
VDEFGINTDN MFGFWDWVGG RYSVDSAIGL SVMAAIGRER FAEFLSGFHI
310 320 330 340 350
VDEHFRTAPL EANAPALLGL IGLWYNNFFG AQSRAVLPYS NDLSRFAAYL
360 370 380 390 400
QQLTMESNGK SVRADGTPVI TDTGEIFWGE PGTNGQHAFY QLLHQGTRLV
410 420 430 440 450
PADFIGFSQP TDDLATADGA GSMHDLLMSN FFAQTQVLAF GKTAEEIADE
460 470 480 490 500
GTPPEVVPHK VMPGNRPSTS ILAAKLTPSV VGQLIALYEH QVFTEGVIWG
510 520 530 540 550
IDSFDQWGVE LGKTQAKALL PVLTADASPA QQSDSSTDAL VRRYRVERGR

PA
Length:552
Mass (Da):60,012
Last modified:January 18, 2017 - v1
Checksum:iAC7732B54E8B4967
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MIGZ01000089 Genomic DNA. Translation: ODQ92840.1.
RefSeqiWP_069406079.1. NZ_MIGZ01000089.1.

Genome annotation databases

EnsemblBacteriaiODQ92840; ODQ92840; BHQ17_15625.

Similar proteinsi

Entry informationi

Entry nameiA0A1E3RSL9_9MYCO
AccessioniPrimary (citable) accession number: A0A1E3RSL9
Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: September 27, 2017
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported