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Protein

dCTP deaminase

Gene

dcd

Organism
Campylobacter jejuni
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the deamination of dCTP to dUTP.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

dCTP + H2O = dUTP + NH3.UniRule annotation

Pathwayi: dUMP biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes dUMP from dCTP (dUTP route).UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. dCTP deaminase (dcd), dCTP deaminase (dcd), dCTP deaminase (dcd), dCTP deaminase (dcd), dCTP deaminase (dcd), dCTP deaminase (dcd), dCTP deaminase (dcd), dCTP deaminase (dcd)
  2. no protein annotated in this organism
This subpathway is part of the pathway dUMP biosynthesis, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes dUMP from dCTP (dUTP route), the pathway dUMP biosynthesis and in Pyrimidine metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei133Proton donor/acceptorUniRule annotation1
Binding sitei152dCTPUniRule annotation1
Binding sitei166dCTPUniRule annotation1
Binding sitei172dCTPUniRule annotation1
Binding sitei176dCTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi107 – 112dCTP bindingUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processNucleotide metabolismUniRule annotationSAAS annotation
LigandNucleotide-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00610; UER00665

Names & Taxonomyi

Protein namesi
Recommended name:
dCTP deaminaseUniRule annotationSAAS annotation (EC:3.5.4.13UniRule annotation)
Alternative name(s):
Deoxycytidine triphosphate deaminaseUniRule annotation
Gene namesi
Name:dcdUniRule annotation
ORF Names:B5Y32_03840Imported, BD28_06270Imported, BKM79_06455Imported
OrganismiCampylobacter jejuniImported
Taxonomic identifieri197 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000194235 Componenti: Unassembled WGS sequence
  • UP000186418 Componenti: Chromosome

Interactioni

Subunit structurei

Homotrimer.UniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 178dUTPaseInterPro annotationAdd BLAST101

Sequence similaritiesi

Belongs to the dCTP deaminase family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd07557 trimeric_dUTPase, 1 hit
Gene3Di2.70.40.10, 1 hit
HAMAPiMF_00146 dCTP_deaminase, 1 hit
InterProiView protein in InterPro
IPR011962 dCTP_deaminase
IPR029054 dUTPase-like
IPR036157 dUTPase-like_sf
IPR033704 dUTPase_trimeric
PfamiView protein in Pfam
PF00692 dUTPase, 1 hit
SUPFAMiSSF51283 SSF51283, 1 hit
TIGRFAMsiTIGR02274 dCTP_deam, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1D9BMJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLKADNWIR KMALEHKMIE PFCEANIGKG VVSYGLSSYG YDIRVGREFK
60 70 80 90 100
IFTNVNSTVV DPKNFVEENV VDFEGDVCIV PANSFALART IEYFKMPDNV
110 120 130 140 150
LAICLGKSTY ARCGIIVNVT PFEPGFEGHI TIEISNTTPL PAKIYANEGI
160 170 180
AQVLFLQGDE KCDTTYKDKK GKYQAQTGIT LPRILK
Length:186
Mass (Da):20,699
Last modified:January 18, 2017 - v1
Checksum:i68DC660FB28FD33C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017673 Genomic DNA Translation: AOY03440.1
CP007189 Genomic DNA Translation: APU79881.1
NAAF01000006 Genomic DNA Translation: OSY77267.1
RefSeqiWP_002854086.1, NZ_PECP01000007.1

Genome annotation databases

PATRICifig|197.5165.peg.1263

Similar proteinsi

Entry informationi

Entry nameiA0A1D9BMJ1_CAMJU
AccessioniPrimary (citable) accession number: A0A1D9BMJ1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: June 20, 2018
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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