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Protein
Submitted name:

Transducin like enhancer of split 4

Gene

TLE4

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transducin like enhancer of split 4Imported
Gene namesi
Name:TLE4Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini515 – 688WD_REPEATS_REGIONInterPro annotationAdd BLAST174
Repeati605 – 646WDPROSITE-ProRule annotationAdd BLAST42
Repeati647 – 688WDPROSITE-ProRule annotationAdd BLAST42
Domaini729 – 805WD_REPEATS_REGIONInterPro annotationAdd BLAST77
Repeati729 – 760WDPROSITE-ProRule annotationAdd BLAST32

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili32 – 59Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, WD repeatPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00550000074465

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR005617 Groucho/TLE_N
IPR009146 Groucho_enhance
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF03920 TLE_N, 1 hit
PF00400 WD40, 2 hits
PRINTSiPR01850 GROUCHOFAMLY
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 2 hits

Sequencei

Sequence statusi: Complete.

A0A1D5RAC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRDLSKMYP QTRHPAPHQP AQPFKFTISE SCDRIKEEFQ FLQAQYHSLK
60 70 80 90 100
LECEKLASEK TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVIP
110 120 130 140 150
FLSQEHQQQV VQAVERAKQV TMAELNAIIG QQLQAQHLSH GHGLPVPLTP
160 170 180 190 200
HPSGLQPPAI PPIGSSAGLL ALSSALGGQS HLPIKDEKKH HDNDHQRDRD
210 220 230 240 250
SIKSSSVSPS ASFRGAEKHR NSTDYSSESK KQKTEEKEIA ARYDSDGEKS
260 270 280 290 300
DDNLVVDVSN EDPSSPRGSP AHSPRENGLD KTRLLKKDAP ISPASIASSS
310 320 330 340 350
STPSSKSKEL SLKRDMGKLS ETRLSEDEKC TLGLQRWFCR LWFMNEKSTT
360 370 380 390 400
PVSKSNTPTP RTDAPTPGSN STPGLRPVPG KPPGVDPLAS SLRTPMAVPC
410 420 430 440 450
PYPTPFGIVP HAGMNGELTS PGAAYAGLHN ISPQMSAAAA AAAAAAAYGR
460 470 480 490 500
SPVVGFDPHH HMRVPAIPPN LTGIPGGKPA YSFHVSADGQ MQPVPFPPDA
510 520 530 540 550
LIGPGIPRHA RQINTLNHGE VVCAVTISNP TRHVYTGGKG CVKVWDISHP
560 570 580 590 600
GNKSPVSQLD CLNRDNYIRS CRLLPDGRTL IVGGEASTLS IWDLAAPTPR
610 620 630 640 650
IKAELTSSAP ACYALAISPD SKVCFSCCSD GNIAVWDLHN QTLVRQFQGH
660 670 680 690 700
TDGASCIDIS NDGTKLWTGG LDNTVRSWDL REGRQLQQHD FTSQIFSLGY
710 720 730 740 750
CPTGEWLAVG MENSNVEVLH VTKPDKYQLH LHESCVLSLK FAHCGKWFVS
760 770 780 790 800
TGKDNLLNAW RTPYGASIFQ SKESSSVLSC DISVDDKYIV TGSGDKKATV

YEVIY
Length:805
Mass (Da):87,732
Last modified:November 30, 2016 - v1
Checksum:iD4A911E3352E2151
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03015400 Genomic DNA No translation available.
RefSeqiXP_001103029.2, XM_001103029.3
UniGeneiMmu.19930

Genome annotation databases

EnsembliENSMMUT00000077328; ENSMMUP00000057269; ENSMMUG00000023365
GeneIDi706619

Similar proteinsi

Entry informationi

Entry nameiA0A1D5RAC8_MACMU
AccessioniPrimary (citable) accession number: A0A1D5RAC8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2016
Last sequence update: November 30, 2016
Last modified: June 20, 2018
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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