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Protein

DNA ligase

Gene

PCHCB_000425500

Organism
Plasmodium chabaudi chabaudi
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PCHCB_000425500Imported
OrganismiPlasmodium chabaudi chabaudiImported
Taxonomic identifieri31271 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Vinckeia)

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500892061718 – 891DNA ligaseSequence analysisAdd BLAST874

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini622 – 758DNA_LIGASE_A3InterPro annotationAdd BLAST137

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di1.10.3260.10, 2 hits
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1D3S2L4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLLLVLLT KMYFCKIKRY MRTEYNYVTP FMKSKLFHNY KNKFNVIIVK
60 70 80 90 100
NIRNNVPNRN DKYLKCLSFP KKMEGDEQCD TKVEETHVKS EEKEVSKRKN
110 120 130 140 150
TNDDGTKTKK PKGKNENEIK KGSLFNCKVY EDEKISDLAS PKFNPANFDI
160 170 180 190 200
SNLCLPEKDK AKHKFKDSLL FTFLTNTFNQ IEELKGSGAG SKKNVAIILS
210 220 230 240 250
NVFRVLIYYS PNDLIPAVYI TLNKVAPDYQ NVEAGVGEAL ILKTMSEAYS
260 270 280 290 300
RTEASIKKDL QQIEDLGIIA ESCSCKMRTI FPLPRLTIQS VFNELKSIPN
310 320 330 340 350
ISGSNSQQKK REVIKKLLVS AKTSEAKYIV RFLQQRLRIG VNSATVLQAL
360 370 380 390 400
AYAFVLTRPE LPENIIKEGK LMNEKLLNES VAVKGDNATE IKNENNIKSE
410 420 430 440 450
KKNDADNKTS ALDTDQFNDL VKSIKMRNER MSKPNLFYNI GKEGDTRLLR
460 470 480 490 500
IFKELKNAYC DVNNDSDIFE CMEKSVKSAL CELPNIEMII QNLLNGDDMN
510 520 530 540 550
VLMKKCTVKT GVPVQPMLAK PTKGIQEVLD RFNNVTFTCE YKYDGERAQI
560 570 580 590 600
HYIDKDNIKI FSRNLETMTE KYPDVIQIVK DQIMPGVTES IIDSEVVAYD
610 620 630 640 650
IENKKILPFQ ILTTRKRKDV DIENIKVKIC LFPFDLICCN GVPVIKEPLE
660 670 680 690 700
IRRKLLYSLL KCKEGVLEYA THSEMNNIED IDMFLQDAIE NSCEGLMVKT
710 720 730 740 750
LLDNASYEPS RRSLNWLKVK KDYIEGLSDS VDLVPIAGYY GKGKRSGVYG
760 770 780 790 800
AFVLAAYNSE TENFQTVCKA GTGFSDEILN ALHESLSDKI IPNKKSYYEV
810 820 830 840 850
SDKLNPDVWF DAHYVWEIKA ADLSLSPVHT AAIGVYSDDK GIGLRFPRFL
860 870 880 890
RLRDDKNPEQ ATTTQQIVEF YEAQFASNKN KNNYNDDSGS E
Length:891
Mass (Da):101,718
Last modified:November 30, 2016 - v1
Checksum:i27B6BE143831C2E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LT608166 Genomic DNA Translation: SCN62599.1

Similar proteinsi

Entry informationi

Entry nameiA0A1D3S2L4_PLACH
AccessioniPrimary (citable) accession number: A0A1D3S2L4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2016
Last sequence update: November 30, 2016
Last modified: May 23, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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