Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamate-1-semialdehyde 2,1-aminomutase

Gene

hemL

Organism
Methanosphaera sp. WGK6
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

(S)-4-amino-5-oxopentanoate = 5-aminolevulinate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferaseImported, IsomeraseUniRule annotationImported, Transferase
Biological processPorphyrin biosynthesisUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-1-semialdehyde 2,1-aminomutaseUniRule annotation (EC:5.4.3.8UniRule annotation)
Short name:
GSAUniRule annotation
Alternative name(s):
Glutamate-1-semialdehyde aminotransferaseUniRule annotation
Short name:
GSA-ATUniRule annotation
Gene namesi
Name:hemLUniRule annotation
ORF Names:NL43_02045Imported
OrganismiMethanosphaera sp. WGK6Imported
Taxonomic identifieri1561964 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanosphaera
Proteomesi
  • UP000094737 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei262N6-(pyridoxal phosphate)lysineUniRule annotation1

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.UniRule annotation

Family and domain databases

CDDicd00610 OAT_like, 1 hit
Gene3Di3.40.640.101 hit
3.90.1150.102 hits
HAMAPiMF_00375 HemL_aminotrans_3, 1 hit
InterProiView protein in InterPro
IPR004639 4pyrrol_synth_GluAld_NH2Trfase
IPR005814 Aminotrans_3
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00202 Aminotran_3, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR00713 hemL, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1D2X398-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFDKSKKLY EEAVNYLPGG VNSPIRAYKP YPFFAKRAKG SKIYDEDGNE
60 70 80 90 100
FIDYCLGYGP IIFGHANETI VEESIKQLQL GTDYGVPSEK EISLAKEVIK
110 120 130 140 150
RVPSAEMVRF TNSGTEATMS AIRLARGITG RNKIIKFEGA YHGAHDAVLV
160 170 180 190 200
KSGSGAAGKP DSPGIPEDTT KNTILVPFND EDELTRIIKE NKEEIACIII
210 220 230 240 250
EPIMGNIGCV PPKDDYLTFL REITEENDIL LIIDEVITGF RISKGGAQKY
260 270 280 290 300
YNVTPDLCTF GKILGGGFPI GAIAGKKEYM EQFTPSGTIY QAGTFSGNPM
310 320 330 340 350
SINGGLTAFK ILDDKFYKDL HNKGEYFRNE IRAILNKLDI NYQVNGVESM
360 370 380 390 400
TQIYFTNKEV YDYKTAQTTD TKGFLKYFHN LLENGVFIAP SQYECTFLSC
410 420
AHSMEDIDKT IESIEISLKN I
Length:421
Mass (Da):46,910
Last modified:November 30, 2016 - v1
Checksum:i499D41C067B0451F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JRWK01000003 Genomic DNA Translation: OED30431.1
RefSeqiWP_069592387.1, NZ_JRWK01000003.1

Genome annotation databases

EnsemblBacteriaiOED30431; OED30431; NL43_02045
PATRICifig|1561964.3.peg.399

Similar proteinsi

Entry informationi

Entry nameiA0A1D2X398_9EURY
AccessioniPrimary (citable) accession number: A0A1D2X398
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2016
Last sequence update: November 30, 2016
Last modified: April 25, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported