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Protein

Phospho-N-acetylmuramoyl-pentapeptide-transferase

Gene

mraY

Organism
Aliivibrio sp. 1S175
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported
Biological processCell cycle, Cell divisionUniRule annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotation, Peptidoglycan synthesisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferaseUniRule annotation (EC:2.7.8.13UniRule annotation)
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferaseUniRule annotation
Gene namesi
Name:mraYUniRule annotation
ORF Names:A6E06_15015Imported
OrganismiAliivibrio sp. 1S175Imported
Taxonomic identifieri1840087 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
Proteomesi
  • UP000093290 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 41HelicalUniRule annotationAdd BLAST20
Transmembranei73 – 91HelicalUniRule annotationAdd BLAST19
Transmembranei97 – 114HelicalUniRule annotationAdd BLAST18
Transmembranei134 – 152HelicalUniRule annotationAdd BLAST19
Transmembranei172 – 193HelicalUniRule annotationAdd BLAST22
Transmembranei200 – 219HelicalUniRule annotationAdd BLAST20
Transmembranei239 – 256HelicalUniRule annotationAdd BLAST18
Transmembranei263 – 284HelicalUniRule annotationAdd BLAST22
Transmembranei290 – 311HelicalUniRule annotationAdd BLAST22
Transmembranei338 – 357HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family. MraY subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

CDDicd06852 GT_MraY, 1 hit
HAMAPiMF_00038 MraY, 1 hit
InterProiView protein in InterPro
IPR000715 Glycosyl_transferase_4
IPR003524 PNAcMuramoyl-5peptid_Trfase
IPR018480 PNAcMuramoyl-5peptid_Trfase_CS
PANTHERiPTHR22926 PTHR22926, 1 hit
PfamiView protein in Pfam
PF00953 Glycos_transf_4, 1 hit
PF10555 MraY_sig1, 1 hit
TIGRFAMsiTIGR00445 mraY, 1 hit
PROSITEiView protein in PROSITE
PS01347 MRAY_1, 1 hit
PS01348 MRAY_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1B9PNP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIWLSNFLE QYFPFFRLFE YLSFRAILSI ITALSISLWM GPKLIRWLQN
60 70 80 90 100
LQIGQVVRDD GPESHFSKRG TPTMGGIMIL TAISVTVFLW ADLTNPYVWA
110 120 130 140 150
VMFVLLGYGA VGFVDDYRKV VRKNTDGLIA RWKYFWQSAI ALVVAFALYA
160 170 180 190 200
YGKDTAATQL VVPFFKDIMP QLGLTYILLT YFVIVGTSNA VNLTDGLDGL
210 220 230 240 250
AIMPTVFVAA GFAFIAWATG NVQFANYLHI PHIPQASELV VVCAAIVGAG
260 270 280 290 300
FGFLWFNTYP AQVFMGDVGS LALGGALGTI AVLVRQEFLL VIMGGVFVVE
310 320 330 340 350
TLSVILQVGS YKLRGQRIFR MAPIHHHYEL KGWPEPRVIV RFWIISMLLV
360
LIALATLKVR
Length:360
Mass (Da):40,194
Last modified:November 2, 2016 - v1
Checksum:i3ABD100BBA9425DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MAJS01000010 Genomic DNA Translation: OCH34933.1
RefSeqiWP_065591369.1, NZ_MAJS01000010.1

Genome annotation databases

EnsemblBacteriaiOCH34933; OCH34933; A6E06_15015

Similar proteinsi

Entry informationi

Entry nameiA0A1B9PNP8_9GAMM
AccessioniPrimary (citable) accession number: A0A1B9PNP8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2016
Last sequence update: November 2, 2016
Last modified: September 27, 2017
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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