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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Enterococcus faecalis (Streptococcus faecalis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei140GTPUniRule annotation1
Binding sitei144GTPUniRule annotation1
Binding sitei188GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 26GTPUniRule annotation5
Nucleotide bindingi109 – 111GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
ORF Names:A6B47_04440Imported, BHU49_07905Imported, BZG32_05185Imported, CEQ17_006295Imported, CEQ25_009640Imported, CYR78_05965Imported, ELS84_1697Imported
OrganismiEnterococcus faecalis (Streptococcus faecalis)Imported
Taxonomic identifieri1351 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
Proteomesi
  • UP000197555 Componenti: Unassembled WGS sequence
  • UP000196367 Componenti: Chromosome
  • UP000177536 Componenti: Unassembled WGS sequence
  • UP000197838 Componenti: Unassembled WGS sequence
  • UP000234629 Componenti: Unassembled WGS sequence
  • UP000193511 Componenti: Unassembled WGS sequence
  • UP000187983 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 206TubulinInterPro annotationAdd BLAST193
Domaini208 – 325Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1B4XMH3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFSLDNNIN NGAVIKVIGV GGGGGNAVNR MIEENVKGVE FITANTDVQA
60 70 80 90 100
LKHSKAETVI QLGPKYTRGL GAGSQPEVGQ KAAEESEQVI SESLQGADMI
110 120 130 140 150
FITAGMGGGT GTGAAPVVAK IAKELGALTV GVVTRPFSFE GPKRGRFAAE
160 170 180 190 200
GIALLKENVD TLLIISNNRL LEVVDKKTPM LEAFREADNV LRQGVQGISD
210 220 230 240 250
LITAPGYVNL DFADVKTVME NQGTALMGIG VASGEERVIE ATKKAISSPL
260 270 280 290 300
LETSIDGAEQ VLLNITGGLD MTLFEAQDAS DIVTNAASGD VNIILGTSIN
310 320 330 340 350
EDLGDEIRVT VIATGIDESK KDRKPHRQTR QAVQPMQQTT QSVEMDQPKS
360 370 380 390 400
QEEASAFGDW DIRREQNTRP KVDESSLEQV DKKEFDTFHR EEPNHNDDEL
410
STPPFFRRKR
Length:410
Mass (Da):44,148
Last modified:November 2, 2016 - v1
Checksum:i63DDD649B8369D61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP019512 Genomic DNA. Translation: AQL53131.1.
CP015883 Genomic DNA. Translation: ARV03140.1.
MJEK01000058 Genomic DNA. Translation: OGX74906.1.
MSQH01000015 Genomic DNA. Translation: OSH09479.1.
PKGH01000014 Genomic DNA. Translation: PLA96727.1.
NJFO02000003 Genomic DNA. Translation: PNK94882.1.
NJFK02000001 Genomic DNA. Translation: PNL20244.1.
RefSeqiWP_002355899.1. NZ_PGCH01000004.1.

Genome annotation databases

PATRICifig|1351.219.peg.629.

Similar proteinsi

Entry informationi

Entry nameiA0A1B4XMH3_ENTFL
AccessioniPrimary (citable) accession number: A0A1B4XMH3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2016
Last sequence update: November 2, 2016
Last modified: March 28, 2018
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported