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Protein

Glucose-6-phosphate isomerase

Gene

pgi1

Organism
Rhodococcus opacus (Nocardia opaca)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi1), Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi4)
  3. ATP-dependent 6-phosphofructokinase (pfkA), ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei386UniRule annotation1
Active sitei512UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgi1Imported
Synonyms:pgiUniRule annotation
ORF Names:R1CP_09220Imported
OrganismiRhodococcus opacus (Nocardia opaca)Imported
Taxonomic identifieri37919 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesNocardiaceaeRhodococcus
Proteomesi
  • UP000186108 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd05015. SIS_PGI_1. 1 hit.
cd05016. SIS_PGI_2. 1 hit.
Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase. 1 hit.
InterProiView protein in InterPro
IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
IPR035476. SIS_PGI_1.
IPR035482. SIS_PGI_2.
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiView protein in Pfam
PF00342. PGI. 1 hit.
PRINTSiPR00662. G6PISOMERASE.
PROSITEiView protein in PROSITE
PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1B1K1S0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDITGTAA WQKLRDHHAQ IQSVHLRELF EKDPARGQEL TVSAGDLYID
60 70 80 90 100
YSKHRIDRDT IGLLLELARS ADLEARRDAM FAGEHINTSE DRAVLHTALR
110 120 130 140 150
LPADASLVVD GQDVVADVHD VLDRMGDFTD RVRSGEWRGA TGERIKTVVN
160 170 180 190 200
IGIGGSDLGP VMVYRALRHY ADAGISVRFI SNVDPADLVR SLQGLDPATT
210 220 230 240 250
LFIVASKTFS TLETLTNATA ARRWLLGGLG LGNEAVAKHF VAVSTHADRV
260 270 280 290 300
AEFGIDTANM FGFWDWVGGR YSVDSAIGLS VMAAIGKERF AEFLAGFHAV
310 320 330 340 350
DEHFRTAPLE ENAPVLLGLI GLWYSNFFGA ESRAVLPYSN DLVRFPAYLQ
360 370 380 390 400
QLTMESNGKS VRADGSPVPT STGEIFWGEP GTNGQHAFYQ LLHQGTRLVP
410 420 430 440 450
SDFIGFGEPT DDLPTADGTG SMHDLLMSNF FAQTKVLAFG KTAEEIAAEG
460 470 480 490 500
TPENLVPHKV MPGNRPSTTI LAPKLTPSVI GQLIALYEHQ VFVEGVVWGI
510 520 530 540 550
DSFDQWGVEL GKTQAVELQP VLTAADEPAA QSDSSTDSLV RWYRRQRGRA
Length:550
Mass (Da):59,974
Last modified:November 2, 2016 - v1
Checksum:iBB6E58FE92AF8CD6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009111 Genomic DNA. Translation: ANS26564.1.
RefSeqiWP_065489949.1. NZ_CP009111.1.

Genome annotation databases

PATRICifig|37919.13.peg.1898.

Similar proteinsi

Entry informationi

Entry nameiA0A1B1K1S0_RHOOP
AccessioniPrimary (citable) accession number: A0A1B1K1S0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2016
Last sequence update: November 2, 2016
Last modified: September 27, 2017
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported