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Protein
Submitted name:

Voltage-dependent L-type calcium channel subunit alpha-1D

Gene

CACNA1D

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent L-type calcium channel subunit alpha-1DImported
Gene namesi
Name:CACNA1DImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:1391 CACNA1D

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei90 – 116HelicalSequence analysisAdd BLAST27
Transmembranei170 – 188HelicalSequence analysisAdd BLAST19
Transmembranei200 – 219HelicalSequence analysisAdd BLAST20
Transmembranei261 – 283HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000157388

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A1B0GWF7

Expressioni

Gene expression databases

ExpressionAtlasiA0A1B0GWF7 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 123Ion_transInterPro annotationAdd BLAST88
Domaini166 – 222Ion_transInterPro annotationAdd BLAST57
Domaini229 – 284Ion_transInterPro annotationAdd BLAST56

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00830000128247

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR005452 LVDCC_a1dsu
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR10037:SF139 PTHR10037:SF139, 2 hits
PfamiView protein in Pfam
PF00520 Ion_trans, 3 hits

Sequencei

Sequence statusi: Fragment.

A0A1B0GWF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XFYRCTDEAK SNPEECRGLF ILYKDGDVDS PVVRERIWQN SDFNFDNVLS
60 70 80 90 100
AMMALFTVST FEGWPALLYK AIDSNGENIG PIYNHRVEIS IFFIIYIIIV
110 120 130 140 150
AFFMMNIFVG FVIVTFQEQG EKEYKNCELD KNQRQCVEYA LKARPLRRYI
160 170 180 190 200
PKNPYQYKFW YVVNSSPFEY MMFVLIMLNT LCLAMQHYEQ SKMFNDAMDI
210 220 230 240 250
LNMVFTGVFT VEMVLKVIAF KPKNSEESNR ISITFFRLFR VMRLVKLLSR
260 270 280
GEGIRTLLWT FIKSFQALPY VALLIAMLFF IYAV
Length:284
Mass (Da):33,506
Last modified:October 5, 2016 - v1
Checksum:i932B6F85BA8F409C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei284Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005905 Genomic DNA No translation available.
AC012467 Genomic DNA No translation available.
AC024149 Genomic DNA No translation available.
AC092035 Genomic DNA No translation available.
AC112218 Genomic DNA No translation available.
AC132810 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000636723; ENSP00000490908; ENSG00000157388

Similar proteinsi

Entry informationi

Entry nameiA0A1B0GWF7_HUMAN
AccessioniPrimary (citable) accession number: A0A1B0GWF7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: May 23, 2018
This is version 12 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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