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Protein
Submitted name:

Transcription factor 7-like 2

Gene

TCF7L2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor 7-like 2Imported
Gene namesi
Name:TCF7L2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:11641. TCF7L2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000148737.

Expressioni

Gene expression databases

ExpressionAtlasiA0A1B0GVE1. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 116CTNNB1_bindingInterPro annotationAdd BLAST83

Phylogenomic databases

GeneTreeiENSGT00390000009964.

Family and domain databases

InterProiView protein in InterPro
IPR013558. CTNNB1-bd_N.
IPR024940. TCF/LEF.
PANTHERiPTHR10373. PTHR10373. 1 hit.
PfamiView protein in Pfam
PF08347. CTNNB1_binding. 1 hit.

Sequencei

Sequence statusi: Fragment.

A0A1B0GVE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYPRDTILVG MEDLSGKGGA VASGVSLFQQ LGGWHLNLNC WSNKVPVVQH
60 70 80 90 100
PHHVHPLTPL ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY
110 120 130 140
PLSPGTVGQI PHPLGWQGQP VYPITTGGFR HPYPTALTVN A
Length:141
Mass (Da):15,261
Last modified:October 5, 2016 - v1
Checksum:iAC277E735377CF21
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei141Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135792 Genomic DNA. No translation available.
AL158212 Genomic DNA. No translation available.
AL445486 Genomic DNA. No translation available.
AL451084 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000637574; ENSP00000490478; ENSG00000148737.

Similar proteinsi

Entry informationi

Entry nameiA0A1B0GVE1_HUMAN
AccessioniPrimary (citable) accession number: A0A1B0GVE1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: October 25, 2017
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported