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Protein
Submitted name:

Transcription factor 7-like 2

Gene

TCF7L2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1 – 69HMG boxCuratedAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingCurated

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor 7-like 20 Publication
Gene namesi
Name:TCF7L20 Publication
OrganismiHomo sapiens (Human)0 Publication
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:11641. TCF7L2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusCurated

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000148737.

Expressioni

Gene expression databases

ExpressionAtlasiA0A1B0GUV5. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 69HMG boxImportedAdd BLAST69

Phylogenomic databases

GeneTreeiENSGT00390000009964.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiView protein in InterPro
IPR009071. HMG_box_dom.
IPR036910. HMG_box_dom_sf.
IPR024940. TCF/LEF.
PANTHERiPTHR10373. PTHR10373. 1 hit.
PfamiView protein in Pfam
PF00505. HMG_box. 1 hit.
SMARTiView protein in SMART
SM00398. HMG. 1 hit.
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiView protein in PROSITE
PS50118. HMG_BOX_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

A0A1B0GUV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IKKPLNAFML YMKEMRAKVV AECTLKESAA INQILGRRWH ALSREEQAKY
60 70 80 90 100
YELARKERQL HMQLYPGWSA RDNYGKKKKR KRDKQPGETN GEKKSAFATY
110
KVKAAASAHP LQMEAY
Length:116
Mass (Da):13,534
Last modified:October 5, 2016 - v1
Checksum:iE7F71657F4DA9E95
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei10 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135792 Genomic DNA. No translation available.
AL158212 Genomic DNA. No translation available.
AL445486 Genomic DNA. No translation available.
AL451084 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000466338; ENSP00000490260; ENSG00000148737.

Similar proteinsi

Entry informationi

Entry nameiA0A1B0GUV5_HUMAN
AccessioniPrimary (citable) accession number: A0A1B0GUV5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: October 25, 2017
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.0 Publication

Keywords - Technical termi

Complete proteome, Reference proteome0 Publication