UniProtKB - A0A1A8ABH1 (A0A1A8ABH1_NOTFU)
(max 400 entries)x
Your basket is currently empty. i
Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)
Protein
NADPH:adrenodoxin oxidoreductase, mitochondrial
Gene
FDXR
Organism
Nothobranchius furzeri (Turquoise killifish)
Status
Functioni
Catalytic activityi
2 reduced adrenodoxin + NADP+ = 2 oxidized adrenodoxin + NADPH.UniRule annotation
Cofactori
FADUniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 42 | FAD; via amide nitrogenUniRule annotation | 1 | |
Binding sitei | 63 | FADUniRule annotation | 1 | |
Binding sitei | 71 | FAD; via amide nitrogenUniRule annotation | 1 | |
Binding sitei | 107 | FAD; via amide nitrogen and carbonyl oxygenUniRule annotation | 1 | |
Binding sitei | 234 | NADPUniRule annotation | 1 | |
Binding sitei | 392 | FAD; via amide nitrogenUniRule annotation | 1 | |
Binding sitei | 399 | NADP; via amide nitrogenUniRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 178 – 181 | NADPUniRule annotation | 4 | |
Nucleotide bindingi | 222 – 223 | NADPUniRule annotation | 2 | |
Nucleotide bindingi | 399 – 401 | FADUniRule annotation | 3 |
GO - Molecular functioni
- NADPH-adrenodoxin reductase activity Source: UniProtKB-EC
Keywordsi
Molecular function | OxidoreductaseUniRule annotation |
Ligand | FADUniRule annotation, Flavoprotein, NADPUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: NADPH:adrenodoxin oxidoreductase, mitochondrialUniRule annotation (EC:1.18.1.6UniRule annotation) |
Gene namesi | Name:FDXRImported |
Organismi | Nothobranchius furzeri (Turquoise killifish)Imported |
Taxonomic identifieri | 105023 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Neoteleostei › Acanthomorphata › Ovalentaria › Atherinomorphae › Cyprinodontiformes › Nothobranchiidae › Nothobranchius |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 33 – 189 | FAD/NAD-binding_domInterPro annotationAdd BLAST | 157 |
Sequence similaritiesi
Belongs to the ferredoxin--NADP reductase type 1 family.UniRule annotation
Phylogenomic databases
KOi | K18914. |
Family and domain databases
Gene3Di | 3.50.50.60. 2 hits. |
InterProi | View protein in InterPro IPR036188. FAD/NAD-bd_sf. IPR023753. FAD/NAD-binding_dom. IPR021163. Ferredox_Rdtase_adrenod. |
Pfami | View protein in Pfam PF07992. Pyr_redox_2. 1 hit. |
PIRSFi | PIRSF000362. FNR. 1 hit. |
i Sequence
Sequence statusi: Complete.
A0A1A8ABH1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSCKLLLSAV GRRRLHKGFA VCGKAFLSSG SPKVCIVGSG PAGFYTAQHL
60 70 80 90 100
LKAHQNVQVD VYERLPVPFG LVRFGVAPDH PEVKNVINTF TQTAKHPRCS
110 120 130 140 150
FYGNVNVGED VSVDELQEAY HAIVLSYGAE GNRSVGVPGE DLPGVYSAKD
160 170 180 190 200
FVGWYNGLPS CQELRPDLSC ETAVILGQGN VALDVARILL SPLDALKKTD
210 220 230 240 250
ITQPALEALA QSRVCRVLIV GRRGPMQVAS TIKELREMVN LPGTRPEMVA
260 270 280 290 300
ADFDGVAEAL KDLPRPRKRL TELMLKTALE MPTEKEQERR KKASRIWGFR
310 320 330 340 350
FFRSPVEILA EPGCNRVAGV RLAVNKLEGS GEKAQAVLTG EVEDVPCGLV
360 370 380 390 400
ISSIGYRSLP IDPTVPFDSR RAIVPNSMGR VHNAAGLYCS GWLKTGPTGV
410 420 430 440 450
IATTMNSSFD TARSLLEDVE SGKLDVSSAK PGSHMISSLL EKRGVKPVTF
460 470 480
SDWEKIDDLE TRRGEVSGKP REKILTVAAM LKVAQT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HADY01013543 Transcribed RNA. Translation: SBP52028.1. HAEJ01017801 Transcribed RNA. Translation: SBS58258.1. |
RefSeqi | XP_015819225.1. XM_015963739.1. |
Genome annotation databases
GeneIDi | 107388287. |
KEGGi | nfu:107388287. |
Similar proteinsi
Entry informationi
Entry namei | A0A1A8ABH1_NOTFU | |
Accessioni | A0A1A8ABH1Primary (citable) accession number: A0A1A8ABH1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 5, 2016 |
Last sequence update: | October 5, 2016 | |
Last modified: | March 28, 2018 | |
This is version 10 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |