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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mycobacterium sp. 1482292.6
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:A5624_09895Imported
OrganismiMycobacterium sp. 1482292.6Imported
Taxonomic identifieri1834081 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000092339 Componenti: Unassembled WGS sequence

Subcellular locationi

A0A1A3DLA5:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 93Arg_tRNA_synt_NInterPro annotationAdd BLAST90
Domaini429 – 554DALR_1InterPro annotationAdd BLAST126

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi130 – 140"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1A3DLA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPADLAELL KTTAAAVLAE RGLDAAALPP TVTVERPRNP EHGDYASNLA
60 70 80 90 100
LQLGKKVGAN PRDLAGWLAE ALASAAGVAS AEVAGPGFIN LRLEASAQAV
110 120 130 140 150
VVTNVIDAGD RYGHSDALAG RNINLEFVSA NPTGPIHIGG TRWAAVGDAL
160 170 180 190 200
GRLLATQGAA VVREYYFNDH GAQIDRFASS LIAAAKGEPT PEDGYAGAYI
210 220 230 240 250
NDIAAQVLQK APDALSLPDG EMRETFREIG VDLMFTHIKE SLHEFGTDFD
260 270 280 290 300
VYTHEDSMHT KGLVDQAIGR LRETGNIYEK DGATWLRTSA FGDDKDRVVI
310 320 330 340 350
KSDGKPAYIA GDIAYYLDKR QRGFDLAIYM LGADHHGYIA RLKAVAAAFG
360 370 380 390 400
DDPAAVEVLI GQMVNLVRDG QPVRMSKRAG TVITLDDLVE AIGVDAARYS
410 420 430 440 450
LIRSSVDTPI DIDLALWSSA SNENPVYYVQ YAHARLSALA RNAAELGLVP
460 470 480 490 500
GGAGFEGHLE LLSHDKEGTL LRTIGEFPRV LDTAATLREP HRVCRYLEDL
510 520 530 540 550
AGDYHRFYDS CRVLPQGDEQ PSDLHTARLA LCQATRQVIA NGLAILGVTA

PERM
Length:554
Mass (Da):59,474
Last modified:October 5, 2016 - v1
Checksum:iA9796A9CED8F87FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LZKV01000266 Genomic DNA. Translation: OBI99650.1.

Genome annotation databases

EnsemblBacteriaiOBI99650; OBI99650; A5624_09895.

Similar proteinsi

Entry informationi

Entry nameiA0A1A3DLA5_9MYCO
AccessioniPrimary (citable) accession number: A0A1A3DLA5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: October 25, 2017
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported