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Protein

Transcription termination factor Rho

Gene

rho

Organism
Mycobacterium mungi
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei387ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi344 – 349ATPUniRule annotation6
Nucleotide bindingi356 – 361ATPUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotation, Hydrolase, RNA-bindingUniRule annotation
Biological processTranscription, Transcription regulation, Transcription terminationUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription termination factor RhoUniRule annotation (EC:3.6.4.-UniRule annotation)
Alternative name(s):
ATP-dependent helicase RhoUniRule annotation
Gene namesi
Name:rhoUniRule annotation
ORF Names:A7J32_03465Imported
OrganismiMycobacterium mungiImported
Taxonomic identifieri1844474 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000078489 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Homohexamer. The homohexamer assembles into an open ring structure.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA0A197J3R0
SMRiA0A197J3R0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 78Rho_NInterPro annotationAdd BLAST43
Domaini227 – 288CSPInterPro annotationAdd BLAST62
Domaini345 – 530AAAInterPro annotationAdd BLAST186

Sequence similaritiesi

Belongs to the Rho family.UniRule annotation

Family and domain databases

HAMAPiMF_01884 Rho, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR011129 CSD
IPR012340 NA-bd_OB-fold
IPR027417 P-loop_NTPase
IPR011112 Rho_N
IPR036269 Rho_N_sf
IPR011113 Rho_RNA-bd
IPR004665 Term_rho
PANTHERiPTHR15184:SF34 PTHR15184:SF34, 1 hit
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF07498 Rho_N, 1 hit
PF07497 Rho_RNA_bind, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00357 CSP, 1 hit
SM00959 Rho_N, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF52540 SSF52540, 1 hit
SSF68912 SSF68912, 1 hit
TIGRFAMsiTIGR00767 rho, 1 hit

Sequencei

Sequence statusi: Complete.

A0A197J3R0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDTDLITAG ESTDGKPSDA AATDPPDLNA DEPAGSLATM VLPELRALAN
60 70 80 90 100
RAGVKGTSGM RKNELIAAIE EIRRQANGAP AVDRSAQEHD KGDRPPSSEA
110 120 130 140 150
PATQGEQTPT EQIDSQSQQV RPERRSATRE AGPSGSGERA GTAADDTDNR
160 170 180 190 200
QGGQQDAKTE ERGTDAGGDQ GGDQQASGGQ QARGDEDGEA RQGRRGRRFR
210 220 230 240 250
DRRRRGERSG DGAEAELRED DVVQPVAGIL DVLDNYAFVR TSGYLPGPHD
260 270 280 290 300
VYVSMNMVRK NGMRRGDAVT GAVRVPKEGE QPNQRQKFNP LVRLDSINGG
310 320 330 340 350
SVEDAKKRPE FGKLTPLYPN QRLRLETSTE RLTTRVIDLI MPIGKGQRAL
360 370 380 390 400
IVSPPKAGKT TILQDIANAI TRNNPECHLM VVLVDERPEE VTDMQRSVKG
410 420 430 440 450
EVIASTFDRP PSDHTSVAEL AIERAKRLVE QGKDVVVLLD SITRLGRAYN
460 470 480 490 500
NASPASGRIL SGGVDSTALY PPKRFLGAAR NIEEGGSLTI IATAMVETGS
510 520 530 540 550
TGDTVIFEEF KGTGNAELKL DRKIAERRVF PAVDVNPSGT RKDELLLSPD
560 570 580 590 600
EFAIVHKLRR VLSGLDSHQA IDLLMSQLRK TKNNYEFLVQ VSKTTPGSMD

SD
Length:602
Mass (Da):65,133
Last modified:October 5, 2016 - v1
Checksum:i4E77B200810AE57F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LXTB01000030 Genomic DNA Translation: OAQ19079.1
RefSeqiWP_003898814.1, NZ_LXTB01000030.1

Genome annotation databases

EnsemblBacteriaiOAQ19079; OAQ19079; A7J32_03465

Similar proteinsi

Entry informationi

Entry nameiA0A197J3R0_9MYCO
AccessioniPrimary (citable) accession number: A0A197J3R0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: October 25, 2017
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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