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Protein

Histone deacetylase

Gene
N/A
Organism
Anopheles melas
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.SAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri637 – 699UBP-typePROSITE-ProRule annotationAdd BLAST63

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorSAAS annotation, HydrolaseSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseSAAS annotation (EC:3.5.1.98SAAS annotation)
OrganismiAnopheles melasImported
Taxonomic identifieri34690 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000075902 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500813739325 – 743Histone deacetylaseSequence analysisAdd BLAST719

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini637 – 699UBP-typeInterPro annotationAdd BLAST63

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri637 – 699UBP-typePROSITE-ProRule annotationAdd BLAST63

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PF02148. zf-UBP. 1 hit.
PRINTSiPR01270. HDASUPER.
SMARTiView protein in SMART
SM00290. ZnF_UBP. 1 hit.
PROSITEiView protein in PROSITE
PS50271. ZF_UBP. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A182TVE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEITPAFYSH LLSPLLLMAQ GRVAVVLEGG YCLESLAEGC ALTLKTLLGD
60 70 80 90 100
PAPRLAEALQ PPSESMQASI LNCIYSHRKY WKCLQLYELY DLEDYNNTNP
110 120 130 140 150
QDNFHKVIKC YVPPEPPAQP GRYETRNCYP VQSADERARI QDRLARLHLA
160 170 180 190 200
TDLSFPPDRV CFVYDELMLE HRNSAEKWHP EQPERIAKIM QRLTGDYQLA
210 220 230 240 250
QRMKRLPGRL ATTEELCLVH GPEHVRLIGE VCQSSTMKQA ADQYNSIYFH
260 270 280 290 300
PSTDASARMA TGSVLTVVED VLEGRTRSGV CVVRPPGHHA EADTPHGFCI
310 320 330 340 350
YNSIAVAARH AVKRYGLRRV LIVDWDVHHG NGTQHIFEQD PHVLYISVHR
360 370 380 390 400
YDNGAFFPRS TDADYTVVGS GPGRGFNVNI PWNRKGMGDP EYVAAFHSVI
410 420 430 440 450
LPIAYEYEPE VVLVSAGFDA AIGDPLGGCR VTPEAYGHFT QWLSVLAGGR
460 470 480 490 500
LVLCLEGGYN VNSISHAMAM CAKALLGDPL PMLLPVSGTA RTPPATHASC
510 520 530 540 550
CETLWNVLSV QRLYWRSLCF NKKLPSSEPL LEETGSELIE ALDNMTLSER
560 570 580 590 600
GGTDQQQPQQ TTSSTPSSSS AATAGSSGGE QAGSSSKKSS QTLTEFLEAN
610 620 630 640 650
LEALQNEEMF AVIPRRDCPH LKLLRPETAP EAIDTRTPCS DCGAEVENWI
660 670 680 690 700
CLLCFGVYCG RYVNEHMLQH GTGAADHPLA LSFADLSVWC YGCDAYIDHP
710 720 730 740
ALHHYKNLVH QDKFHEPLVW SYGSDLVLDV VPGSSTGRKA GQD
Length:743
Mass (Da):82,139
Last modified:September 7, 2016 - v1
Checksum:i84D4EB3DE6AE01EF
GO

Genome annotation databases

VectorBaseiAMEC008982-RA; AMEC008982-PA; AMEC008982.

Similar proteinsi

Entry informationi

Entry nameiA0A182TVE2_9DIPT
AccessioniPrimary (citable) accession number: A0A182TVE2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 7, 2016
Last sequence update: September 7, 2016
Last modified: August 30, 2017
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported