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Protein

Probable malate:quinone oxidoreductase

Gene

mqo1

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotationSAAS annotation

Cofactori

FADUniRule annotationSAAS annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo2), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo2), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo2), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo2), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo2), Probable malate:quinone oxidoreductase (mqo2), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo1)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotationImported
Biological processTricarboxylic acid cycleUniRule annotationSAAS annotation
LigandFADUniRule annotationSAAS annotation, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqo1Imported
Synonyms:mqoUniRule annotation
ORF Names:SAMEA2236422_01003Imported, SAMEA2236459_00749Imported, SAMEA2384800_01329Imported, SAMEA2384856_01340Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.50.50.602 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

A0A181EZ61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTQHSKTDV ILIGGGIMSA TLGTLLKELS PEKNIKVFEK LAQPGEESSN
60 70 80 90 100
VWNNAGTGHS ALCELNYTKE GKDGTVDCSK AIKINEQYQI SKQFWAYLVK
110 120 130 140 150
TGQLDNPDRF IQAVPHMSFV IGEDNVAFIK SRVATLKKSI LFEKMKLSQD
160 170 180 190 200
EEEMKSWVPL MIEGRKSDEP IALTYDETGT DVNFGALTAK LFDNLEQRGV
210 220 230 240 250
GIQYKQNVLD IKKQKSGVWL VKVKDLETNE TTTYESDFVF IGAGGASLPL
260 270 280 290 300
LQKTGIKQSK HIGGFPVSGL FLRCINQEVI DRHHAKVYGK AAVGAPPMSV
310 320 330 340 350
PHLDTRFVDG KRSLLFGPFA GFSPKFLKTG SHMDLIKSVK PNNIVTMLSA
360 370 380 390 400
GIKEMSLTKY LVSQLMLSND ERMDDLRVFF PNAKNEDWEV ITAGQRVQVI
410 420 430 440 450
KDIEDSKGNL QFGTEVITSD DGTLAALLGA SPGASTAVDI MFDVLQRCYR
460 470 480 490
DEFKGWEPKI KEMVPSFGYR LTDHEDLYHK INEEVTKYLQ VK
Length:492
Mass (Da):54,838
Last modified:September 7, 2016 - v1
Checksum:i307F42FDEE3061D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FKMV01000003 Genomic DNA Translation: SAZ00018.1
FKMG01000002 Genomic DNA Translation: SAZ52410.1
FKVM01000004 Genomic DNA Translation: SBE15306.1
FKWA01000004 Genomic DNA Translation: SBE36665.1
RefSeqiWP_000211358.1, NZ_NHZX01000003.1

Genome annotation databases

PATRICifig|1280.4348.peg.121

Similar proteinsi

Entry informationi

Entry nameiA0A181EZ61_STAAU
AccessioniPrimary (citable) accession number: A0A181EZ61
Entry historyiIntegrated into UniProtKB/TrEMBL: September 7, 2016
Last sequence update: September 7, 2016
Last modified: March 28, 2018
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)