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Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Streptomyces sp. F-3
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei68Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processDNA damage, DNA repairUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
Short name:
UDGUniRule annotation
Gene namesi
Name:ungUniRule annotation
ORF Names:STXM2123_780Imported
OrganismiStreptomyces sp. F-3Imported
Taxonomic identifieri1840095 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000078145 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 212UDGInterPro annotationAdd BLAST160

Sequence similaritiesi

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd10027. UDG_F1. 1 hit.
Gene3Di3.40.470.10. 1 hit.
HAMAPiMF_00148. UDG. 1 hit.
InterProiView protein in InterPro
IPR002043. UDG_fam1.
IPR018085. Ura-DNA_Glyclase_AS.
IPR005122. Uracil-DNA_glycosylase-like.
IPR036895. Uracil-DNA_glycosylase-like_sf.
PANTHERiPTHR11264. PTHR11264. 1 hit.
PfamiView protein in Pfam
PF03167. UDG. 1 hit.
SMARTiView protein in SMART
SM00986. UDG. 1 hit.
SUPFAMiSSF52141. SSF52141. 1 hit.
PROSITEiView protein in PROSITE
PS00130. U_DNA_GLYCOSYLASE. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A170V4N9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRPLHELV EAGWAKALEP VAGRIAEMGD FLRAEVAAGR TYLPAGHHVL
60 70 80 90 100
RAFQQPFDEV KVLIVGQDPY PTPGMAIGLS FAVSPEVRSL PGSLENIYRE
110 120 130 140 150
LTADLGLPRP SNGDLTPWTR QGVLLLNRAL TTAPRRPGAH RGKGWEEVTD
160 170 180 190 200
QAIRALVARG RPLVSILWGR DARSLRPLLG PYPAIESAHP SPMSADRGFF
210 220
GSRPFSRANE LLVQQGAEPV DWRLP
Length:225
Mass (Da):24,640
Last modified:July 6, 2016 - v1
Checksum:i9C16F8EA01271403
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BDDR01000004 Genomic DNA. Translation: GAT80079.1.

Genome annotation databases

EnsemblBacteriaiGAT80079; GAT80079; STXM2123_780.

Similar proteinsi

Entry informationi

Entry nameiA0A170V4N9_9ACTN
AccessioniPrimary (citable) accession number: A0A170V4N9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 6, 2016
Last sequence update: July 6, 2016
Last modified: March 28, 2018
This is version 15 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported